5mr9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Ligand-receptor complex.== | |
| - | + | <StructureSection load='5mr9' size='340' side='right' caption='[[5mr9]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5mr9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MR9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MR9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mr9 OCA], [http://pdbe.org/5mr9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mr9 RCSB], [http://www.ebi.ac.uk/pdbsum/5mr9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mr9 ProSAT]</span></td></tr> | |
| - | [[ | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN]] Hirschsprung disease. Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.<ref>PMID:9700200</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN]] Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Aagaard, A]] | [[Category: Aagaard, A]] | ||
| + | [[Category: Dahl, G]] | ||
[[Category: Oster, L]] | [[Category: Oster, L]] | ||
| - | + | [[Category: Roth, R G]] | |
| - | [[Category: Roth, R | + | |
[[Category: Sandmark, J]] | [[Category: Sandmark, J]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Receptor]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Signalling]] | ||
Revision as of 06:48, 17 January 2018
Ligand-receptor complex.
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Categories: Aagaard, A | Dahl, G | Oster, L | Roth, R G | Sandmark, J | Complex | Receptor | Signaling protein | Signalling
