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5k9c

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==Crystal structure of human dihydroorotate dehydrogenase with ML390==
==Crystal structure of human dihydroorotate dehydrogenase with ML390==
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<StructureSection load='5k9c' size='340' side='right' caption='[[5k9c]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
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<StructureSection load='5k9c' size='340' side='right'caption='[[5k9c]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5k9c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K9C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K9C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5k9c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K9C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5K9C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FNR:1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL'>FNR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLJ:~{N}-[3-OXIDANYLIDENE-3-[[(1~{R})-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL]AMINO]PROPYL]-4-(TRIFLUOROMETHYLOXY)BENZAMIDE'>MLJ</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FNR:1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL'>FNR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLJ:~{N}-[3-OXIDANYLIDENE-3-[[(1~{R})-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL]AMINO]PROPYL]-4-(TRIFLUOROMETHYLOXY)BENZAMIDE'>MLJ</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k9d|5k9d]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k9d|5k9d]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DHODH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_dehydrogenase_(quinone) Dihydroorotate dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.5.2 1.3.5.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_dehydrogenase_(quinone) Dihydroorotate dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.5.2 1.3.5.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k9c OCA], [http://pdbe.org/5k9c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k9c RCSB], [http://www.ebi.ac.uk/pdbsum/5k9c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k9c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5k9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k9c OCA], [http://pdbe.org/5k9c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k9c RCSB], [http://www.ebi.ac.uk/pdbsum/5k9c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k9c ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5k9c" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5k9c" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Law, J M]]
[[Category: Law, J M]]
[[Category: Lewis, T A]]
[[Category: Lewis, T A]]

Revision as of 09:28, 1 July 2020

Crystal structure of human dihydroorotate dehydrogenase with ML390

PDB ID 5k9c

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