This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Botulinum neurotoxin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 52: Line 52:
*Type A receptor-binding domain
*Type A receptor-binding domain
-
**[[2vua]], [[3fuo]] – CbPBN <br />
+
**[[2vua]], [[3fuo]], [[5tpb]], [[5tpc]] – CbPBN <br />
**[[4iqp]] – CbPBN (mutant)<br />
**[[4iqp]] – CbPBN (mutant)<br />
**[[2vu9]] – CbPBN + polysaccharide + Mg<br />
**[[2vu9]] – CbPBN + polysaccharide + Mg<br />
-
**[[4jra]] – CbCBN + synaptic vesicle glycoprotein 2C<br />
+
**[[4jra]], [[5jlv]] – CbCBN + synaptic vesicle glycoprotein 2C<br />
 +
**[[5jmc]] – CbCBN (mutant) + synaptic vesicle glycoprotein 2C<br />
 +
**[[4zjx]] – CbCBN + polypeptide inhibitor<br />
*Type A Light+Heavy Chain translocation domain
*Type A Light+Heavy Chain translocation domain
Line 100: Line 102:
**[[3rmx]], [[3rmy]] – CbCBN (mutant) <br />
**[[3rmx]], [[3rmy]] – CbCBN (mutant) <br />
**[[3obt]] - CbCBN + acetylneuraminic acid<br />
**[[3obt]] - CbCBN + acetylneuraminic acid<br />
 +
**[[5bqm]] – CbCBN + somatoliberin<br />
 +
 +
*Type D LHN domain
 +
 +
**[[5bqn]] - CbCBN <br />
*Type E
*Type E
-
**[[3ffz]] – CbCBN + Zn<br />
+
**[[3ffz]], [[4zkt]] – CbCBN + Zn<br />
*Type E Light Chain
*Type E Light Chain

Revision as of 09:53, 22 March 2017

Clostridium botulinum neurotoxin type A with cofactor Zn+2 (grey) (PDB code 3bta).

Drag the structure with the mouse to rotate

3D structures of botulinum neurotoxin

Updated on 22-March-2017


References

  1. ↑ Montecucco C, Molgo J. Botulinal neurotoxins: revival of an old killer. Curr Opin Pharmacol. 2005 Jun;5(3):274-9. PMID:15907915 doi:http://dx.doi.org/10.1016/j.coph.2004.12.006
  2. ↑ Lacy DB, Tepp W, Cohen AC, DasGupta BR, Stevens RC. Crystal structure of botulinum neurotoxin type A and implications for toxicity. Nat Struct Biol. 1998 Oct;5(10):898-902. PMID:9783750 doi:10.1038/2338

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Botulinum_neurotoxin"
Personal tools