Botulinum neurotoxin
From Proteopedia
(Difference between revisions)
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*Type A receptor-binding domain | *Type A receptor-binding domain | ||
| - | **[[2vua]], [[3fuo]] | + | **[[2vua]], [[3fuo]], [[5tpb]], [[5tpc]] – CbPBN <br /> |
**[[4iqp]] – CbPBN (mutant)<br /> | **[[4iqp]] – CbPBN (mutant)<br /> | ||
**[[2vu9]] – CbPBN + polysaccharide + Mg<br /> | **[[2vu9]] – CbPBN + polysaccharide + Mg<br /> | ||
| - | **[[4jra]] – CbCBN + synaptic vesicle glycoprotein 2C<br /> | + | **[[4jra]], [[5jlv]] – CbCBN + synaptic vesicle glycoprotein 2C<br /> |
| + | **[[5jmc]] – CbCBN (mutant) + synaptic vesicle glycoprotein 2C<br /> | ||
| + | **[[4zjx]] – CbCBN + polypeptide inhibitor<br /> | ||
*Type A Light+Heavy Chain translocation domain | *Type A Light+Heavy Chain translocation domain | ||
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**[[3rmx]], [[3rmy]] – CbCBN (mutant) <br /> | **[[3rmx]], [[3rmy]] – CbCBN (mutant) <br /> | ||
**[[3obt]] - CbCBN + acetylneuraminic acid<br /> | **[[3obt]] - CbCBN + acetylneuraminic acid<br /> | ||
| + | **[[5bqm]] – CbCBN + somatoliberin<br /> | ||
| + | |||
| + | *Type D LHN domain | ||
| + | |||
| + | **[[5bqn]] - CbCBN <br /> | ||
*Type E | *Type E | ||
| - | **[[3ffz]] – CbCBN + Zn<br /> | + | **[[3ffz]], [[4zkt]] – CbCBN + Zn<br /> |
*Type E Light Chain | *Type E Light Chain | ||
Revision as of 09:53, 22 March 2017
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3D structures of botulinum neurotoxin
Updated on 22-March-2017
References
- ↑ Montecucco C, Molgo J. Botulinal neurotoxins: revival of an old killer. Curr Opin Pharmacol. 2005 Jun;5(3):274-9. PMID:15907915 doi:http://dx.doi.org/10.1016/j.coph.2004.12.006
- ↑ Lacy DB, Tepp W, Cohen AC, DasGupta BR, Stevens RC. Crystal structure of botulinum neurotoxin type A and implications for toxicity. Nat Struct Biol. 1998 Oct;5(10):898-902. PMID:9783750 doi:10.1038/2338
