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5ug4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae== | |
| - | + | <StructureSection load='5ug4' size='340' side='right' caption='[[5ug4]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ug4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UG4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UG4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diamine_N-acetyltransferase Diamine N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.57 2.3.1.57] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ug4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ug4 OCA], [http://pdbe.org/5ug4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ug4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ug4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ug4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ATDA_VIBCH ATDA_VIBCH]] Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine.<ref>PMID:23184347</ref> <ref>PMID:25623305</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Diamine N-acetyltransferase]] | ||
| + | [[Category: Anderson, W F]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Filippova, E V]] | ||
| + | [[Category: Kiryukhina, O]] | ||
[[Category: Minasov, G]] | [[Category: Minasov, G]] | ||
| - | [[Category: Kiryukhina, O]] | ||
| - | [[Category: Filippova, E.V]] | ||
| - | [[Category: Anderson, W.F]] | ||
| - | [[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]] | ||
[[Category: Shuvalova, L]] | [[Category: Shuvalova, L]] | ||
| + | [[Category: Csgid]] | ||
| + | [[Category: Speg]] | ||
| + | [[Category: Spermidine]] | ||
| + | [[Category: Spermine]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 23:48, 25 January 2017
Structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae
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