5wqc

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'''Unreleased structure'''
 
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The entry 5wqc is ON HOLD until Paper Publication
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==Crystal structure of human orexin 2 receptor bound to the selective antagonist EMPA determined by the synchrotron light source at SPring-8.==
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<StructureSection load='5wqc' size='340' side='right' caption='[[5wqc]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5wqc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WQC FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7MA:N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide'>7MA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wqc OCA], [http://pdbe.org/5wqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wqc RCSB], [http://www.ebi.ac.uk/pdbsum/5wqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wqc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN]] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
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__TOC__
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</StructureSection>
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[[Category: Hirata, K]]
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[[Category: Horita, S]]
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[[Category: Iwata, S]]
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[[Category: Kobayashi, T]]
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[[Category: Rosenbaum, D M]]
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[[Category: Sasanuma, M]]
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[[Category: Shimamura, T]]
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[[Category: Suno, R]]
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[[Category: Tsujimoto, H]]
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[[Category: Yamamoto, M]]
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[[Category: Yamashita, K]]
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[[Category: Empa]]
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[[Category: G protein-coupled receptor]]
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[[Category: N-linked glycosylation]]
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[[Category: Orexin 2 receptor]]
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[[Category: Orexin neurotransmitter]]
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[[Category: Orexin-a]]
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[[Category: Orexin-b]]
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[[Category: Signaling protein]]

Revision as of 06:12, 29 November 2017

Crystal structure of human orexin 2 receptor bound to the selective antagonist EMPA determined by the synchrotron light source at SPring-8.

5wqc, resolution 1.96Å

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