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5wt5

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'''Unreleased structure'''
 
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The entry 5wt5 is ON HOLD until Paper Publication
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==L-homocysteine-bound NifS from Helicobacter pylori==
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<StructureSection load='5wt5' size='340' side='right' caption='[[5wt5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5wt5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WT5 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wt2|5wt2]], [[5wt4|5wt4]], [[5wt6|5wt6]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_desulfurase Cysteine desulfurase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.7 2.8.1.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt5 OCA], [http://pdbe.org/5wt5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wt5 RCSB], [http://www.ebi.ac.uk/pdbsum/5wt5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ISCS_HELPY ISCS_HELPY]] Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
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__TOC__
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</StructureSection>
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[[Category: Cysteine desulfurase]]
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[[Category: Fujishiro, T]]
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[[Category: Takahashi, Y]]
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[[Category: Iron-sulfur cluster biogenesis]]
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[[Category: Transferase]]

Revision as of 06:59, 13 December 2017

L-homocysteine-bound NifS from Helicobacter pylori

5wt5, resolution 1.90Å

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