RNA polymerase

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- 
<StructureSection load='3m3y' size='350' side='right' caption='Yeast RNA polymerase II elongation complex C complexed with DNA and RNA and Zn+2 (grey) and Mg+2 (green) ions [[3m3y]]. Subunit B1 (grey), B2 (green), B3 (pink), B9 (wheat), B11 (rust), ABC1 (magenta), ABC2 (cyan), ABC3 (red), ABC4 (aqua), ABC5 (blue) (PDB code [[3m3y]]).' scene='RNA_polymerase/Cv/1'>
<StructureSection load='3m3y' size='350' side='right' caption='Yeast RNA polymerase II elongation complex C complexed with DNA and RNA and Zn+2 (grey) and Mg+2 (green) ions [[3m3y]]. Subunit B1 (grey), B2 (green), B3 (pink), B9 (wheat), B11 (rust), ABC1 (magenta), ABC2 (cyan), ABC3 (red), ABC4 (aqua), ABC5 (blue) (PDB code [[3m3y]]).' scene='RNA_polymerase/Cv/1'>
Line 74: Line 73:
**[[4v8s]] – SsRNAP + DNA<br />
**[[4v8s]] – SsRNAP + DNA<br />
**[[3q22]], [[3q23]], [[3q24]], [[4ff1]], [[4ff2]], [[4ff3]], [[4ff4]] – RNAP + DNA – Enterobacteria phage N4<br />
**[[3q22]], [[3q23]], [[3q24]], [[4ff1]], [[4ff2]], [[4ff3]], [[4ff4]] – RNAP + DNA – Enterobacteria phage N4<br />
-
**[[2o5i]], [[2o5j]], [[4gzy]], [[4gzz]] - TtRNAP subunits α,β,β’,ω + DNA +RNA<br />
+
**[[2o5i]], [[2o5j]], [[4gzy]], [[4gzz]], [[4xln]], [[4xlr]] - TtRNAP subunits α,β,β’,ω + DNA +RNA<br />
-
**[[4wqs]] - TtRNAP subunits α,β,β’,ω + DNA<br />
+
**[[4wqs]], [[4xlp]], [[4xlq]], [[4xls]], [[5tjg]] - TtRNAP subunits α,β,β’,ω + DNA<br />
**[[2ppb]] - TtRNAP subunits α,β,β’,ω + antibiotic + DNA + RNA + substrate analog<br />
**[[2ppb]] - TtRNAP subunits α,β,β’,ω + antibiotic + DNA + RNA + substrate analog<br />
**[[4yg2]], [[4jk1]], [[4jk2]], [[4jkr]], [[4kmu]] - EcRNAP subunits α,β,β’,ω + RNA<br />
**[[4yg2]], [[4jk1]], [[4jk2]], [[4jkr]], [[4kmu]] - EcRNAP subunits α,β,β’,ω + RNA<br />
Line 86: Line 85:
**[[3aoh]], [[3aoi]] - TtRNAP subunits α,β,β’,ω + DNA +RNA + GFH1<br />
**[[3aoh]], [[3aoi]] - TtRNAP subunits α,β,β’,ω + DNA +RNA + GFH1<br />
**[[2be5]]- TtRNAP subunits α,β,β’,ω + σ factor + inhibitor <br />
**[[2be5]]- TtRNAP subunits α,β,β’,ω + σ factor + inhibitor <br />
-
**[[2cw0]] - TtRNAP subunits α,β,β’,ω + σ factor<br />
+
**[[2cw0]], [[5tmf]] - TtRNAP subunits α,β,β’,ω + σ factor<br />
**[[3wod]] - TtRNAP subunits α,β,β’,ω + σ factor + GP39<br />
**[[3wod]] - TtRNAP subunits α,β,β’,ω + σ factor + GP39<br />
**[[4mq9]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077<br />
**[[4mq9]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077<br />
 +
**[[5tmc]] - TtRNAP subunits α,β,β’,ω + factor + protein<br />
**[[4oin]], [[4oio]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA<br />
**[[4oin]], [[4oio]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA<br />
**[[4oip]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + nucleotide<br />
**[[4oip]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + nucleotide<br />
**[[4oiq]], [[4oir]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + antibiotic<br />
**[[4oiq]], [[4oir]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + antibiotic<br />
-
**[[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA<br />
+
**[[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[5d4d]], [[5d4e]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA<br />
-
**[[4q5s]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br />
+
**[[4q5s]], [[5d4c]], [[5e17]], [[5e18]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br />
 +
**[[5i2d]] - TtRNAP subunits α,β,β’,ω + factor + transcriptional regulator + DNA + RNA<br />
**[[3dxj]], [[3eql]] - TtRNAP subunits α,β,β’,ω + σ factor + antibiotic<br />
**[[3dxj]], [[3eql]] - TtRNAP subunits α,β,β’,ω + σ factor + antibiotic<br />
**[[4wqt]] - TtRNAP subunits α,β,β’,ω + RNA cleavage stimulating factor<br />
**[[4wqt]] - TtRNAP subunits α,β,β’,ω + RNA cleavage stimulating factor<br />
Line 103: Line 104:
**[[1lb2]], [[3n4m]] - EcRNAP subunit α + DNA + CAP<br />
**[[1lb2]], [[3n4m]] - EcRNAP subunit α + DNA + CAP<br />
**[[1xs9]] - EcRNAP subunit α + DNA + MARA<br />
**[[1xs9]] - EcRNAP subunit α + DNA + MARA<br />
 +
**[[5ciz]] - EcRNAP subunit α + DNA + CRP<br />
**[[3n97]] - EcRNAP subunit α C terminal + DNA + σ factor<br />
**[[3n97]] - EcRNAP subunit α C terminal + DNA + σ factor<br />
-
**[[4ljz]], [[4lk1]], [[4mey]] - EcRNAP subunits α,β,β’,ω + RNAP sigma factor <br />
+
**[[4ljz]], [[4lk1]], [[4mey]], [[4xsx]], [[4xsy]], [[4xsz]], [[4zh2]], [[4zh3]] , [[4zh4]], [[5byh]], [[5nwt]], [[5uag]], [[5uah]], [[5uaj]], [[5ual]], [[5uaq]] - EcRNAP subunits α,β,β’,ω + σ factor <br />
-
**[[4mex]] - EcRNAP subunits α,β,β’,ω + RNAP sigma factor + salinamide<br />
+
**[[5nsr]], [[5nss]] - EcRNAP subunits α,β,β’,ω + sigma factor + DNA – Cryo EMbr />
-
**[[4lk0]], [[4llg]] - EcRNAP subunits α,β,β’,ω + RNAP sigma factor + RNAP inhibitor<br />
+
**[[4yln]], [[4ylo]], [[4ylp]], [[5ipl]], [[5ipm]], [[5ipn]] - EcRNAP subunits α,β,β’,ω + RNAP sigma factor + DNA + RNA<br />
-
**[[3iyd]] - EcRNAP subunits α,β,β’,ω + RNAP sigma factor + catabolite gene activator + DNA<br />
+
**[[4mex]] - EcRNAP subunits α,β,β’,ω + σ factor + salinamide<br />
-
**[[4s20]] - EcRNAP subunits α,β,β’,ω + RNAP sigma factor + RAPA + DNA<br />
+
**[[4lk0]], [[4llg]], [[4mex]], [[4yfk]], [[4yfn]], [[4yfx]] - EcRNAP subunits α,β,β’,ω + σ factor + RNAP inhibitor<br />
 +
**[[5uac]] - EcRNAP subunits α,β,β’,ω + sigma factor + rifampin<br />
 +
**[[3iyd]] - EcRNAP subunits α,β,β’,ω + σ factor + catabolite gene activator + DNA<br />
 +
**[[4s20]] - EcRNAP subunits α,β,β’,ω + σ factor + RAPA + DNA<br />
 +
**[[5tbz]] - EcRNAP subunits α,β,β’ + NusG – Cryo EM<br />
 +
**[[5ms0]] - EcRNAP subunits α,β,β’,ω + sigma factor + NusB + NusG + NusA + antitermination protein + DNA – Cryo EM<br />
**[[3ihq]], [[1z3e]], [[3gfk]] - BsRNAP subunit α +regulatory protein SPX
**[[3ihq]], [[1z3e]], [[3gfk]] - BsRNAP subunit α +regulatory protein SPX
**[[1l9u]] - TaRNAP subunits α,β,β’,ω + σ factor<br />
**[[1l9u]] - TaRNAP subunits α,β,β’,ω + σ factor<br />
Line 125: Line 132:
**[[1a1d]] – yRNAP subunit RPB8 – yeast - NMR<br />
**[[1a1d]] – yRNAP subunit RPB8 – yeast - NMR<br />
**[[2rf4]] - yRNAP I subunit RPA4<br />
**[[2rf4]] - yRNAP I subunit RPA4<br />
 +
**[[5g5l]], [[5lmx]], [[5m3f]], [[5m3m]], [[5m5w]], [[5m5x]], [[5m5y]], [[5m64]] – yRNAP I – Cryo EM<br />
 +
**[[5n5y]], [[5n5z]], [[5n60]], [[5oa1]] – yRNAP I + RRN – Cryo EM<br />
 +
**[[5n61]] – yRNAP I + RRN + DNA + RNA – Cryo EM<br />
*Eukaryotic DNA-dependent RNAP II
*Eukaryotic DNA-dependent RNAP II
Line 133: Line 143:
**[[2ghq]], [[2ght]] - hRNAP II subunits RPB1 + hRNAP II C terminal<br />
**[[2ghq]], [[2ght]] - hRNAP II subunits RPB1 + hRNAP II C terminal<br />
**[[2q5e]], [[3l0b]], [[3l0c]] - hRNAP II C terminal<br />
**[[2q5e]], [[3l0b]], [[3l0c]] - hRNAP II C terminal<br />
-
**[[1nik]], [[1nt9]], [[1wcm]], [[2b8k]], [[3fki]], [[3qt1]], [[1i3q]], [[1i50]], [[1dzf]] – yRNAP II<br />
+
**[[1nik]], [[1nt9]], [[1wcm]], [[2b8k]], [[3fki]], [[3qt1]], [[1i3q]], [[1i50]], [[1dzf]], [[5ip7]], [[5ip9]], [[5u5q]] – yRNAP II<br />
-
**[[3j1n]], [[4v1n]] – yRNAP II – Cryo EM<br />
+
**[[4x67]], [[4x6a]], [[4y52]], [[4y7n]], [[5c3e]], [[5c44]], [[5c4a]], [[5c4j]], [[5c4x]] – yRNAP II + DNA + RNA<br />
 +
**[[3j1n]], [[4v1n]], [[5fmf]] – yRNAP II – Cryo EM<br />
**[[1y14]] - yRNAP II subunits RPB4 RPB7<br />
**[[1y14]] - yRNAP II subunits RPB4 RPB7<br />
 +
**[[5flm]] – bRNAP II + DNA + RNA - bovine<br />
 +
**[[5oik]] – bRNAP II + SPT4 + SPT5 + DNA + RNA <br />
 +
**[[3ef0]], [[3ef1]] - fyRNAP II subunit  C terminal – fission yeast<br />
 +
**[[3h0g]] – fyRNAP II<br />
 +
**[[5u0s]] – fyRNAP II + mediator complex – Cryo EM<br />
*Eukaryotic DNA-dependent RNAP III
*Eukaryotic DNA-dependent RNAP III
**[[2xub]], [[2xv4]] - hRNAP III subunits RPC3<br />
**[[2xub]], [[2xv4]] - hRNAP III subunits RPC3<br />
 +
**[[5afq]] - hRNAP III subunits RPC3 + RPC32B<br />
**[[2dk8]] – RNAP III RPC34 domain - mouse – NMR<br />
**[[2dk8]] – RNAP III RPC34 domain - mouse – NMR<br />
**[[2dk5]] – hRNAP III winged helix domain (mutant) – NMR<br />
**[[2dk5]] – hRNAP III winged helix domain (mutant) – NMR<br />
**[[2yu3]] - hRNAP III winged helix domain<br />
**[[2yu3]] - hRNAP III winged helix domain<br />
-
**[[2ckz]]- yRNAP III<br />
+
**[[2ckz]], [[5fj9]], [[5fja]] - yRNAP III<br />
 +
**[[5fj8]]- yRNAP III + DNA + RNA<br />
 +
**[[3ayh]] - fyRNAP III subunit Rpc8+Rpc9<br />
*Eukaryotic DNA-dependent RNAP μ
*Eukaryotic DNA-dependent RNAP μ
**[[4lzd]] – hRNAP μ<br />
**[[4lzd]] – hRNAP μ<br />
-
**[[4lzg]], [[4m04]], [[4m0a]] – hRNAP μ + DNA<br />
+
**[[4lzg]], [[4m04]], [[4m0a]], [[5twp]], [[5twq]], [[5twr]], [[5tws]]. [[5txx]], [[5txz]], [[5tyb]], [[5tyc]], [[5tyd]], [[5tye]], [[5tyf]], [[5tyg]], [[5tyu]], [[5tyv]], [[5tyw]], [[5tyx]], [[5tyy]], [[5tyz]] – hRNAP μ + DNA<br />
*Eukaryotic DNA-dependent RNAP mitochondrial
*Eukaryotic DNA-dependent RNAP mitochondrial
Line 170: Line 189:
**[[3o2q]], [[3o2s]] – hRNAP II subunit α C-terminal + symplekin <br />
**[[3o2q]], [[3o2s]] – hRNAP II subunit α C-terminal + symplekin <br />
-
**[[3j0k]] – hRNAP II + TFIIF – Cryo EM <br />
+
**[[3j0k]], [[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]] – hRNAP II + TFIIF – Cryo EM <br />
**[[2lto]] - hRNAP II subunit RPB1 + Tudor domain containing protein 3<br />
**[[2lto]] - hRNAP II subunit RPB1 + Tudor domain containing protein 3<br />
**[[1pqv]], [[1y1v]], [[4bbr]], [[4bbs]] - yRNAP II + TFIIS<br />
**[[1pqv]], [[1y1v]], [[4bbr]], [[4bbs]] - yRNAP II + TFIIS<br />
**[[1y1y]] - yRNAP II + TFIIS + DNA +RNA <br />
**[[1y1y]] - yRNAP II + TFIIS + DNA +RNA <br />
**[[1r5u]], [[3k7a]], [[3k1f]] - yRNAP II + TFIIB <br />
**[[1r5u]], [[3k7a]], [[3k1f]] - yRNAP II + TFIIB <br />
-
**[[4v1o]] - yRNAP II + DNA + TIIF + TBP + mediator – Cryo EM<br />
+
**[[4v1o]], [[5fyw]], [[5fz5]], [[5sva]] - yRNAP II + DNA + TIIF + TBP + mediator – Cryo EM<br />
**[[2l0i]] – yRNAP C-terminal + RTT103 – NMR<br />
**[[2l0i]] – yRNAP C-terminal + RTT103 – NMR<br />
**[[4bxx]], [[4bxz]], [[4by1]], [[4by7]] – yRNAP II + RNA + DNA + transcription factor Bye1<br />
**[[4bxx]], [[4bxz]], [[4by1]], [[4by7]] – yRNAP II + RNA + DNA + transcription factor Bye1<br />
Line 237: Line 256:
**[[1rdr]] - PoRNAP – Polio virus<br />
**[[1rdr]] - PoRNAP – Polio virus<br />
**[[1tql]], [[2ijd]], [[2ijf]], [[4nlo]], [[4nlp]], [[4nlq]], [[4nlr]], [[4nls]], [[4nlt]], [[4nlu]], [[4nlv]], [[4nlw]], [[4nlx]], [[4nly]], [[4r0e]] - PoRNAP (mutant) <br />
**[[1tql]], [[2ijd]], [[2ijf]], [[4nlo]], [[4nlp]], [[4nlq]], [[4nlr]], [[4nls]], [[4nlt]], [[4nlu]], [[4nlv]], [[4nlw]], [[4nlx]], [[4nly]], [[4r0e]] - PoRNAP (mutant) <br />
-
**[[2xi5]], [[2xi7]] – RNAP L N-terminal – Bunyavirus<br />
+
**[[2xi5]], [[2xi7]] – BvRNAP L N-terminal – Bunyavirus<br />
**[[3jsb]] – RNAP (mutant) – Lymphocytic choriomengitis virus<br />
**[[3jsb]] – RNAP (mutant) – Lymphocytic choriomengitis virus<br />
**[[2wk4]], [[2uut]], [[2uuw]] – SvRNAP (mutant) – Sapporo virus<br />
**[[2wk4]], [[2uut]], [[2uuw]] – SvRNAP (mutant) – Sapporo virus<br />
**[[2ckw]] - SvRNAP residues 1135-1649 <br />
**[[2ckw]] - SvRNAP residues 1135-1649 <br />
**[[3nky]], [[4wyl]], [[4wyw]] - FmRNAP (mutant) - Foot-and-mouth virus<br />
**[[3nky]], [[4wyl]], [[4wyw]] - FmRNAP (mutant) - Foot-and-mouth virus<br />
-
**[[1hhs]], [[4a8o]], [[4b02]], [[1hi8]] – P6RNAP – Bacteriophage φ-6<br />
+
**[[1hhs]], [[4a8o]], [[4b02]], [[1hi8]], [[5fj6]] – P6RNAP – Bacteriophage φ-6<br />
**[[2jl9]], [[2jlf]], [[1wac]] – P6RNAP (mutant) <br />
**[[2jl9]], [[2jlf]], [[1wac]] – P6RNAP (mutant) <br />
 +
**[[5fj7]] – P6RNAP + major inner protein P1 <br />
**[[2po4]] – N4RNAP polymerase domain – Bacteriophage N4<br />
**[[2po4]] – N4RNAP polymerase domain – Bacteriophage N4<br />
**[[1l9k]] – DevRNAP N terminal – Dengue virus<br />
**[[1l9k]] – DevRNAP N terminal – Dengue virus<br />
**[[2j7u]], [[4c11]] - DevRNAP polymerase domain<br />
**[[2j7u]], [[4c11]] - DevRNAP polymerase domain<br />
 +
**[[5ccv]] - DevRNAP NS5<br />
**[[1oks]] – RNAP α subunit – Measles virus<br />
**[[1oks]] – RNAP α subunit – Measles virus<br />
**[[1r4g]] - RNAP α subunit – Sendai virus – NMR<br />
**[[1r4g]] - RNAP α subunit – Sendai virus – NMR<br />
Line 259: Line 280:
**[[2yi8]], [[2yi9]], [[2yia]], [[2yib]] – IpnvRNAP – Infectious pancreatic necrosis virus<br />
**[[2yi8]], [[2yi9]], [[2yia]], [[2yib]] – IpnvRNAP – Infectious pancreatic necrosis virus<br />
**[[3n6l]] – EvRNAP – Human enterovirus<br />
**[[3n6l]] – EvRNAP – Human enterovirus<br />
-
**[[3n6m]], [[3n6n]] – EvRNAP + nucleotide<br />
+
**[[4uci]], [[4ucj]], [[4ucl]], [[4ucy]], [[4ucz]] – HmpvRNAP residues 1600-2005 – Human metapneumovirus<br />
 +
**[[4uck]], [[4ud0]] – HmpvRNAP residues 1600-2005 (mutant)<br />
 +
**[[4zp8]], [[4zp9]], [[4zpa]], [[4zpb]], [[4zpc]], [[4zpd]] – CvRNAP residues 1724-2185 (mutant) – Coxsackievirus<br />
 +
**[[3ddk]] – CvRNAP residues 1724-2185 <br />
**[[3nah]], [[3nai]], [[3qid]], [[3uqs]] – MnvRNAP – Murine norovirus<br />
**[[3nah]], [[3nai]], [[3qid]], [[3uqs]] – MnvRNAP – Murine norovirus<br />
-
**[[3ddk]] – CvRNAP RDRP domain – Coxsakievirus<br />
 
**[[4wfx]], [[4wfy]], [[4wfz]] – CvRNAP RDRP domain (mutant)<br />
**[[4wfx]], [[4wfy]], [[4wfz]] – CvRNAP RDRP domain (mutant)<br />
**[[2j7n]], [[2j7o]] – RNAP residues 381-1402 – Neurospora crassa<br />
**[[2j7n]], [[2j7o]] – RNAP residues 381-1402 – Neurospora crassa<br />
**[[4gzk]], [[4ieg]] – RNAP – cystovirus 12<br />
**[[4gzk]], [[4ieg]] – RNAP – cystovirus 12<br />
**[[4i1t]] – RNAP L – Pichinde virus <br />
**[[4i1t]] – RNAP L – Pichinde virus <br />
-
**[[4miw]] – RNAP L N terminal – Lassa virus <br />
+
**[[5chs]] – RNAP L N-terminal – Vescicular stomatitis Indiana virus <br />
 +
**[[4xha]], [[4xhi]] – TavRNAP – Thosea asigna virus <br />
 +
**[[4miw]], [[5izh]], [[5j1n]], [[5j1p]] – RNAP L N terminal – Lassa virus <br />
**[[4mtp]] – RNAP RDRP module – Encephalitis virus <br />
**[[4mtp]] – RNAP RDRP module – Encephalitis virus <br />
**[[4cgx]], [[4chc]] – TvRNAP N terminal – Thogoto virus <br />
**[[4cgx]], [[4chc]] – TvRNAP N terminal – Thogoto virus <br />
**[[4chd]] – TvRNAP 627 domain <br />
**[[4chd]] – TvRNAP 627 domain <br />
**[[4che]], [[4chf]] – TvRNAP cap-binding domain <br />
**[[4che]], [[4chf]] – TvRNAP cap-binding domain <br />
 +
**[[5fsw]] - NvRNAP C terminal – Thielavia terrestris<br />
 +
**[[5hsb]] – RNAP – Andes virus<br />
 +
**[[5ize]] – RNAP L – Hantaan virus<br />
 +
**[[5ltf]] – LcmvRNAP L – Lymphocytic choriomeningitis mammarenavirus<br />
 +
`**[[5lts]] - LcmvRNAP (mutant)<br />
 +
**[[5u0c]] - ZvRNAP NS5 – Zika virus<br />
*''RNA-dependent RNAP complex with RNA''
*''RNA-dependent RNAP complex with RNA''
Line 277: Line 308:
**[[3ol6]], [[2jlg]], [[4k4s]], [[4k4t]], [[4k4u]], [[4k4v]], [[4k4w]] – PoRNAP (mutant) + RNA <br />
**[[3ol6]], [[2jlg]], [[4k4s]], [[4k4t]], [[4k4u]], [[4k4v]], [[4k4w]] – PoRNAP (mutant) + RNA <br />
**[[3ol7]], [[3ol8]], [[3ol9]], [[3ola]], [[3olb]] - PoRNAP (mutant) + RNA + nucleotide<br />
**[[3ol7]], [[3ol8]], [[3ol9]], [[3ola]], [[3olb]] - PoRNAP (mutant) + RNA + nucleotide<br />
-
**[[3klv]], [[3kmq]], [[3kms]], [[3kna]], [[3nl0]], [[3nma]], [[4iqx]], [[4wzm]] – FmRNAP (mutant) + RNA<br />
+
**[[3klv]], [[3kmq]], [[3kms]], [[3kna]], [[3nl0]], [[3nma]], [[4iqx]], [[4wzm]], [[4wzq]], [[4x2b]], [[5jxs]] – FmRNAP (mutant) + RNA<br />
**[[3koa]] - FmRNAP (mutant) + RNA + nucleotide<br />
**[[3koa]] - FmRNAP (mutant) + RNA + nucleotide<br />
**[[1wne]] – FmRNAP + RNA <br />
**[[1wne]] – FmRNAP + RNA <br />
Line 284: Line 315:
**[[3bsn, [[3bso]], [[3h5x]], [[3h5y]] - NvRNAP + RNA + nucleotide<br />
**[[3bsn, [[3bso]], [[3h5x]], [[3h5y]] - NvRNAP + RNA + nucleotide<br />
**[[2r7r]], [[2r7s]], [[2r7t]], [[2r7u]], [[2r7v]], [[2r7w]], [[2r7x]] – SrRNAP + RNA<br />
**[[2r7r]], [[2r7s]], [[2r7t]], [[2r7u]], [[2r7v]], [[2r7w]], [[2r7x]] – SrRNAP + RNA<br />
 +
**[[5amq]], [[5amr]] – BvRNAP + RNA<br />
**[[4k50]] – RNAP + RNA – Human rhinovirus<br />
**[[4k50]] – RNAP + RNA – Human rhinovirus<br />
**[[3c2p]], [[3c3l]], [[3c46]], [[3q0a]] - N4RNAP polymerase domain + promoter DNA<br />
**[[3c2p]], [[3c3l]], [[3c46]], [[3q0a]] - N4RNAP polymerase domain + promoter DNA<br />

Revision as of 10:50, 31 October 2017

Yeast RNA polymerase II elongation complex C complexed with DNA and RNA and Zn+2 (grey) and Mg+2 (green) ions 3m3y. Subunit B1 (grey), B2 (green), B3 (pink), B9 (wheat), B11 (rust), ABC1 (magenta), ABC2 (cyan), ABC3 (red), ABC4 (aqua), ABC5 (blue) (PDB code 3m3y).

Drag the structure with the mouse to rotate

3D Structures of RNA polymerase

Updated on 31-October-2017

`**5lts - LcmvRNAP (mutant)

References

  1. ↑ Cramer P, Armache KJ, Baumli S, Benkert S, Brueckner F, Buchen C, Damsma GE, Dengl S, Geiger SR, Jasiak AJ, Jawhari A, Jennebach S, Kamenski T, Kettenberger H, Kuhn CD, Lehmann E, Leike K, Sydow JF, Vannini A. Structure of eukaryotic RNA polymerases. Annu Rev Biophys. 2008;37:337-52. doi: 10.1146/annurev.biophys.37.032807.130008. PMID:18573085 doi:http://dx.doi.org/10.1146/annurev.biophys.37.032807.130008
  2. ↑ Comai L. Mechanism of RNA polymerase I transcription. Adv Protein Chem. 2004;67:123-55. PMID:14969726 doi:http://dx.doi.org/10.1016/S0065-3233(04)67005-7
  3. ↑ Hahn S. Structure and mechanism of the RNA polymerase II transcription machinery. Nat Struct Mol Biol. 2004 May;11(5):394-403. PMID:15114340 doi:http://dx.doi.org/10.1038/nsmb763
  4. ↑ Longo DL, Herbert V. Radioassay for serum and red cell folate. J Lab Clin Med. 1976 Jan;87(1):138-51. PMID:1452
  5. ↑ Frick DN, Richardson CC. DNA primases. Annu Rev Biochem. 2001;70:39-80. PMID:11395402 doi:http://dx.doi.org/10.1146/annurev.biochem.70.1.39
  6. ↑ Naue N, Beerbaum M, Bogutzki A, Schmieder P, Curth U. The helicase-binding domain of Escherichia coli DnaG primase interacts with the highly conserved C-terminal region of single-stranded DNA-binding protein. Nucleic Acids Res. 2013 Apr;41(8):4507-17. doi: 10.1093/nar/gkt107. Epub 2013 Feb, 20. PMID:23430154 doi:http://dx.doi.org/10.1093/nar/gkt107
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  8. ↑ Fukushi S, Kojima S, Takai R, Hoshino FB, Oka T, Takeda N, Katayama K, Kageyama T. Poly(A)- and primer-independent RNA polymerase of Norovirus. J Virol. 2004 Apr;78(8):3889-96. PMID:15047805

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