5inj
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5inj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5inj OCA], [http://pdbe.org/5inj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5inj RCSB], [http://www.ebi.ac.uk/pdbsum/5inj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5inj ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5inj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5inj OCA], [http://pdbe.org/5inj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5inj RCSB], [http://www.ebi.ac.uk/pdbsum/5inj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5inj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | This study highlights the biochemical and structural characterization of the L-tryptophan C6 C-prenyltransferase (C-PT) PriB from Streptomyces sp. RM-5-8. PriB was found to be uniquely permissive to a diverse array of prenyl donors and acceptors including daptomycin. Two additional PTs also produced novel prenylated daptomycins with improved antibacterial activities over the parent drug. | ||
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| + | Structure and specificity of a permissive bacterial C-prenyltransferase.,Elshahawi SI, Cao H, Shaaban KA, Ponomareva LV, Subramanian T, Farman ML, Spielmann HP, Phillips GN Jr, Thorson JS, Singh S Nat Chem Biol. 2017 Feb 6. doi: 10.1038/nchembio.2285. PMID:28166207<ref>PMID:28166207</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 5inj" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 06:56, 9 March 2017
Crystal Structure of Prenyltransferase PriB Ternary Complex with L-Tryptophan and Dimethylallyl thiolodiphosphate (DMSPP)
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Categories: Benach, J | Cao, H | Elshahawi, S | Koss, J W | Morisco, L L | NatPro, Enzyme Discovery for Natural Product Biosynthesis | Phillips, G N | Thorson, J S | Wasserman, S R | Abba family | Dmspp | Enzyme discovery for natural product biosynthesis | Indole-pt | Natpro | Prenyltransferase | PSI, Protein structure initiative | Pt fold | Structural genomic | Transferase | Tryptophan
