1rxa

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[[Image:1rxa.gif|left|200px]]
[[Image:1rxa.gif|left|200px]]
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{{Structure
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|PDB= 1rxa |SIZE=350|CAPTION= <scene name='initialview01'>1rxa</scene>, resolution 2.900&Aring;
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The line below this paragraph, containing "STRUCTURE_1rxa", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>
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{{STRUCTURE_1rxa| PDB=1rxa | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rxa OCA], [http://www.ebi.ac.uk/pdbsum/1rxa PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rxa RCSB]</span>
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}}
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'''CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES'''
'''CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES'''
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==About this Structure==
==About this Structure==
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1RXA is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXA OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXA OCA].
==Reference==
==Reference==
The crystal structure of r(CCCCGGGG) in two distinct lattices., Portmann S, Usman N, Egli M, Biochemistry. 1995 Jun 13;34(23):7569-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7779802 7779802]
The crystal structure of r(CCCCGGGG) in two distinct lattices., Portmann S, Usman N, Egli M, Biochemistry. 1995 Jun 13;34(23):7569-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7779802 7779802]
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[[Category: Protein complex]]
 
[[Category: Egli, M.]]
[[Category: Egli, M.]]
[[Category: Portmann, S.]]
[[Category: Portmann, S.]]
[[Category: Usman, N.]]
[[Category: Usman, N.]]
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[[Category: a-rna]]
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[[Category: A-rna]]
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[[Category: double helix]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:00:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:34:15 2008''
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Revision as of 05:00, 3 May 2008

Image:1rxa.gif

Template:STRUCTURE 1rxa

CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES


Overview

The structure of the RNA octamer r(C4G4) has been determined in two different crystal forms. The conformations of the RNA duplex in the rhombohedral and hexagonal lattices display only minimal deviations, demonstrating that the RNA double helix is considerably less deformable than the DNA double helix. For the first time the crystal structures of an A-RNA and an A-DNA with identical sequence can now be compared. The large number of ordered water molecules observed in the minor groove of the RNA duplex suggests that an important contribution to its higher rigidity derives from the improved hydration due to the presence of the 2'-hydroxyl groups. Our finding that the conformation of the RNA double helix is virtually unaffected by different crystal packing modes provides evidence that proteins may not alter the conformation of RNA stem regions in a significant way.

About this Structure

Full crystallographic information is available from OCA.

Reference

The crystal structure of r(CCCCGGGG) in two distinct lattices., Portmann S, Usman N, Egli M, Biochemistry. 1995 Jun 13;34(23):7569-75. PMID:7779802 Page seeded by OCA on Sat May 3 08:00:59 2008

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