1rxq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1rxq.gif|left|200px]]
[[Image:1rxq.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1rxq |SIZE=350|CAPTION= <scene name='initialview01'>1rxq</scene>, resolution 1.70&Aring;
+
The line below this paragraph, containing "STRUCTURE_1rxq", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= yfiT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1rxq| PDB=1rxq | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rxq OCA], [http://www.ebi.ac.uk/pdbsum/1rxq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rxq RCSB]</span>
+
-
}}
+
'''YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology'''
'''YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology'''
Line 29: Line 26:
[[Category: Rajan, S S.]]
[[Category: Rajan, S S.]]
[[Category: Yang, X.]]
[[Category: Yang, X.]]
-
[[Category: helix-bundle]]
+
[[Category: Helix-bundle]]
-
[[Category: hydrolase]]
+
[[Category: Hydrolase]]
-
[[Category: mcsg]]
+
[[Category: Mcsg]]
-
[[Category: midwest center for structural genomic]]
+
[[Category: Midwest center for structural genomic]]
-
[[Category: nickel-binding]]
+
[[Category: Nickel-binding]]
-
[[Category: protein structure initiative]]
+
[[Category: Protein structure initiative]]
-
[[Category: psi]]
+
[[Category: Psi]]
-
[[Category: structural genomic]]
+
[[Category: Structural genomic]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:02:00 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:34:29 2008''
+

Revision as of 05:02, 3 May 2008

Image:1rxq.gif

Template:STRUCTURE 1rxq

YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology


Overview

YfiT, a 19-kDa polypeptide from Bacillus subtilis, belongs to a small sequence family with members predominantly from Gram positive bacteria. We have determined the crystal structure of YfiT in complex with Ni(2+) to a resolution of 1.7 A. YfiT exists as a dimer and binds Ni(2+) in a 1:1 stoichiometry. The protein has an unusual four-helix bundle topology and coordinates Ni(2+) in an octahedral geometry with three conserved histidines and three waters. Although there is no similarity in their overall structures, the coordination geometry of the metal and the residues that constitute the putative active site in YfiT are similar to those of metalloproteases such as thermolysin. Our structural analyses suggest that YfiT might function as a metal-dependent hydrolase.

About this Structure

1RXQ is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology., Rajan SS, Yang X, Shuvalova L, Collart F, Anderson WF, Biochemistry. 2004 Dec 14;43(49):15472-9. PMID:15581359 Page seeded by OCA on Sat May 3 08:02:00 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rxq"
Personal tools