1s03

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1s03.gif|left|200px]]
[[Image:1s03.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1s03 |SIZE=350|CAPTION= <scene name='initialview01'>1s03</scene>, resolution 2.70&Aring;
+
The line below this paragraph, containing "STRUCTURE_1s03", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1s03| PDB=1s03 | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s03 OCA], [http://www.ebi.ac.uk/pdbsum/1s03 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1s03 RCSB]</span>
+
-
}}
+
'''The Structure of a Ribosomal Protein S8/spc Operon mRNA Complex'''
'''The Structure of a Ribosomal Protein S8/spc Operon mRNA Complex'''
Line 28: Line 25:
[[Category: Moore, P B.]]
[[Category: Moore, P B.]]
[[Category: Wang, J.]]
[[Category: Wang, J.]]
-
[[Category: protein-rna complex]]
+
[[Category: Protein-rna complex]]
-
[[Category: ribosomal]]
+
[[Category: Ribosomal]]
-
[[Category: spc operon]]
+
[[Category: Spc operon]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:07:44 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:35:25 2008''
+

Revision as of 05:07, 3 May 2008

Image:1s03.gif

Template:STRUCTURE 1s03

The Structure of a Ribosomal Protein S8/spc Operon mRNA Complex


Overview

In bacteria, translation of all the ribosomal protein cistrons in the spc operon mRNA is repressed by the binding of the product of one of them, S8, to an internal sequence at the 5' end of the L5 cistron. The way in which the first two genes of the spc operon are regulated, retroregulation, is mechanistically distinct from translational repression by S8 of the genes from L5 onward. A 2.8 A resolution crystal structure has been obtained of Escherichia coli S8 bound to this site. Despite sequence differences, the structure of this complex is almost identical to that of the S8/helix 21 complex seen in the small ribosomal subunit, consistent with the hypothesis that autogenous regulation of ribosomal protein synthesis results from conformational similarities between mRNAs and rRNAs. S8 binding must repress the translation of its own mRNA by inhibiting the formation of a ribosomal initiation complex at the start of the L5 cistron.

About this Structure

1S03 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The structure of a ribosomal protein S8/spc operon mRNA complex., Merianos HJ, Wang J, Moore PB, RNA. 2004 Jun;10(6):954-64. PMID:15146079 Page seeded by OCA on Sat May 3 08:07:44 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1s03"
Personal tools