4ofh
From Proteopedia
(Difference between revisions)
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==Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis== | ==Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis== | ||
| - | <StructureSection load='4ofh' size='340' side='right' caption='[[4ofh]], [[Resolution|resolution]] 2.22Å' scene=''> | + | <StructureSection load='4ofh' size='340' side='right'caption='[[4ofh]], [[Resolution|resolution]] 2.22Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ofh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFH FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4ofh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6OG:6-O-METHYL+GUANOSINE-5-MONOPHOSPHATE'>6OG</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6OG:6-O-METHYL+GUANOSINE-5-MONOPHOSPHATE'>6OG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iho|3iho]], [[4ea5|4ea5]], [[4e9g|4e9g]], [[4e9e|4e9e]], [[4e9f|4e9f]], [[4ea4|4ea4]], [[4ofa|4ofa]], [[4ofe|4ofe]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iho|3iho]], [[4ea5|4ea5]], [[4e9g|4e9g]], [[4e9e|4e9e]], [[4e9f|4e9f]], [[4ea4|4ea4]], [[4ofa|4ofa]], [[4ofe|4ofe]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MBD4, MED1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ofh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ofh OCA], [http://pdbe.org/4ofh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ofh RCSB], [http://www.ebi.ac.uk/pdbsum/4ofh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ofh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ofh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ofh OCA], [http://pdbe.org/4ofh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ofh RCSB], [http://www.ebi.ac.uk/pdbsum/4ofh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ofh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lee, S]] | [[Category: Lee, S]] | ||
[[Category: Lin, Y L]] | [[Category: Lin, Y L]] | ||
Revision as of 08:43, 10 April 2019
Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis
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