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4wy6
From Proteopedia
(Difference between revisions)
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<StructureSection load='4wy6' size='340' side='right' caption='[[4wy6]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='4wy6' size='340' side='right' caption='[[4wy6]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4wy6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WY6 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4wy6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WY6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VP:(4AR,6R,8AS)-8A-(2,4-DIFLUOROPHENYL)-6-(FLUOROMETHYL)-4,4A,5,6,8,8A-HEXAHYDROPYRANO[3,4-D][1,3]THIAZIN-2-AMINE'>3VP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VP:(4AR,6R,8AS)-8A-(2,4-DIFLUOROPHENYL)-6-(FLUOROMETHYL)-4,4A,5,6,8,8A-HEXAHYDROPYRANO[3,4-D][1,3]THIAZIN-2-AMINE'>3VP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1, BACE, KIAA1149 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wy6 OCA], [http://pdbe.org/4wy6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wy6 RCSB], [http://www.ebi.ac.uk/pdbsum/4wy6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wy6 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wy6 OCA], [http://pdbe.org/4wy6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wy6 RCSB], [http://www.ebi.ac.uk/pdbsum/4wy6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wy6 ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4wy6" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4wy6" style="background-color:#fffaf0;"></div> | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Beta secretase|Beta secretase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Vajdos, F F]] | [[Category: Vajdos, F F]] | ||
[[Category: Bace beta secretase protease]] | [[Category: Bace beta secretase protease]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 09:30, 22 November 2017
Crystal structure of human BACE-1 bound to Compound 36
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