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4wab
From Proteopedia
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==Crystal structure of mPGES1 solved by native-SAD phasing== | ==Crystal structure of mPGES1 solved by native-SAD phasing== | ||
| - | <StructureSection load='4wab' size='340' side='right' caption='[[4wab]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='4wab' size='340' side='right'caption='[[4wab]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4wab]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WAB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WAB FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4wab]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WAB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WAB FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=LVJ:2-[[2,6-BIS(CHLORANYL)-3-[(2,2-DIMETHYLPROPANOYLAMINO)METHYL]PHENYL]AMINO]-1-METHYL-6-(2-METHYL-2-OXIDANYL-PROPOXY)-N-[2,2,2-TRIS(FLUORANYL)ETHYL]BENZIMIDAZOLE-5-CARBOXAMIDE'>LVJ</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=LVJ:2-[[2,6-BIS(CHLORANYL)-3-[(2,2-DIMETHYLPROPANOYLAMINO)METHYL]PHENYL]AMINO]-1-METHYL-6-(2-METHYL-2-OXIDANYL-PROPOXY)-N-[2,2,2-TRIS(FLUORANYL)ETHYL]BENZIMIDAZOLE-5-CARBOXAMIDE'>LVJ</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LTC4S ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wab OCA], [http://pdbe.org/4wab PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wab RCSB], [http://www.ebi.ac.uk/pdbsum/4wab PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wab ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wab OCA], [http://pdbe.org/4wab PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wab RCSB], [http://www.ebi.ac.uk/pdbsum/4wab PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wab ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4wab" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4wab" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Prostaglandin E synthase|Prostaglandin E synthase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Prostaglandin-E synthase]] | [[Category: Prostaglandin-E synthase]] | ||
[[Category: Caffrey, M]] | [[Category: Caffrey, M]] | ||
Revision as of 09:08, 23 May 2019
Crystal structure of mPGES1 solved by native-SAD phasing
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Categories: Human | Large Structures | Prostaglandin-E synthase | Caffrey, M | Howe, N | Li, D | Wang, M | Weinert, T | Anomalous dispersion | Cancer | Drug target | In meso crystallization | Inflammation | Inhibitor | Isomerase | Leukotriene c4 synthase | Lipid metabolism | Mapag | Membrane protein | Membrane-associated proteins in eicosanoid and glutathione metabolism | Microcrystal | Mpges1 | Native-sad | Pain | S-sad | Sulfur-sad
