This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5lbn
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==High-resolution crystal structure of the UBC core domain of UBE2E1/UbcH6== | |
| - | + | <StructureSection load='5lbn' size='340' side='right' caption='[[5lbn]], [[Resolution|resolution]] 1.42Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5lbn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LBN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbn OCA], [http://pdbe.org/5lbn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lbn RCSB], [http://www.ebi.ac.uk/pdbsum/5lbn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbn ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/UB2E1_HUMAN UB2E1_HUMAN]] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.<ref>PMID:16428300</ref> <ref>PMID:20061386</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Anandapadamanaban, M]] | [[Category: Anandapadamanaban, M]] | ||
| + | [[Category: Moche, M]] | ||
[[Category: Sunnerhagen, M]] | [[Category: Sunnerhagen, M]] | ||
| - | [[Category: | + | [[Category: E2 ubiquitin-conjugating enzyme]] |
| + | [[Category: Transferase]] | ||
| + | [[Category: Ubc core]] | ||
| + | [[Category: Ubiquitination]] | ||
Revision as of 06:21, 15 February 2018
High-resolution crystal structure of the UBC core domain of UBE2E1/UbcH6
| |||||||||||
