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Interactions: When interacting with DNA, the zinc fingers bind in the major groove of B-DNA and wrap part way around the double helix.
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==Interactions==
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The zinc-fingers usually interact with the outside of B-DNA. When interacting with DNA, the zinc fingers bind in the major groove of B-DNA and wrap part way around the double helix.

Revision as of 20:23, 8 February 2017

Zinc-finger 1

Here is a view of the 1zaa structure

Drag the structure with the mouse to rotate


Function

Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. regulate eukaryotic gene expression


Interactions

The zinc-fingers usually interact with the outside of B-DNA. When interacting with DNA, the zinc fingers bind in the major groove of B-DNA and wrap part way around the double helix.

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