Sandbox Reserved 1304
From Proteopedia
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== '''DNA Polymerase IV (PolIV)''' == | == '''DNA Polymerase IV (PolIV)''' == | ||
| - | + | This is <scene name='75/751197/Dna_polymerase_iv/2'>DNA Polymerase IV</scene> as it closely interacts with <scene name='75/751197/Dna/1'>DNA</scene>. | |
| + | <StructureSection load='4irk' size='340' side='right' caption='' scene=''> | ||
== Function == | == Function == | ||
DNA Polymerase IV is a polymerase present only in Escherichia coli (E. Coli), and is involved in non-targeted mutagenesis. PolIV is a Family Y polymerase, expressed by the dinB gene. Its activity is turned on when polymerases at the replication fork become stalled and exhibit SOS induction. It works to create a checkpoint and stop replication, to repair lesions in the DNA. Additionally, Pol IV acts as a trans-lesion synthesizer at a stalled replication fork. | DNA Polymerase IV is a polymerase present only in Escherichia coli (E. Coli), and is involved in non-targeted mutagenesis. PolIV is a Family Y polymerase, expressed by the dinB gene. Its activity is turned on when polymerases at the replication fork become stalled and exhibit SOS induction. It works to create a checkpoint and stop replication, to repair lesions in the DNA. Additionally, Pol IV acts as a trans-lesion synthesizer at a stalled replication fork. | ||
Revision as of 22:14, 9 February 2017
DNA Polymerase IV (PolIV)
This is as it closely interacts with .
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