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''What it interacts with:'' This polymerase interacts with Pol III holoenzyme processivity, and occasionally has been proven to bypass N2-deoxyguanine adducts. It also repairs base-pair lesions, and connects directly to the DNA. | ''What it interacts with:'' This polymerase interacts with Pol III holoenzyme processivity, and occasionally has been proven to bypass N2-deoxyguanine adducts. It also repairs base-pair lesions, and connects directly to the DNA. | ||
| - | ''Where it interacts:'' It acts at stalled replication forks in the DNA of E. Coli; though it is poorly processive, it allows stationary-phase adaptive mutation, which provides the bacterium flexibility in dealing with environmental stress. Ser42 residue in the active site reacts with base pairs on the DNA directly, close to the minor groove. | + | ''Where it interacts:'' It acts at stalled replication forks in the DNA of E. Coli; though it is poorly processive, it allows stationary-phase adaptive mutation, which provides the bacterium flexibility in dealing with environmental stress. <scene name='75/751197/Ser42/1'>Ser42</scene> residue in the active site reacts with base pairs on the DNA directly, close to the minor groove. |
== Origin == | == Origin == | ||
The only organism in which DNA Polymerase IV originates is E. coli bacteria. | The only organism in which DNA Polymerase IV originates is E. coli bacteria. | ||
Revision as of 22:27, 9 February 2017
DNA Polymerase IV (PolIV)
This is as it closely interacts with .
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