Sandbox Reserved 1293

Heterodimer </scene> alignment.

Specific are highlighted here. The ligands listed above, GDP, Phe, and Mg+2 ion each attach at these locations which are still being explored.

which play a crucial role in binding to the ribosome during translation. They form positive pockets with which negative amino acids can bind to.

'Molecules it Interacts With and where '

The protein binds to GDP as well as the following ligands in order to promote the attachment of the protein complex to the ribosome A site.

PHOSHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

PHENYLALANINE MAGNESIUM ION

'Origin'

It has domains that are created in yeast (phenyl-transfer RNA) , in the heat resistant Thermus aquaticus (EF-Tu elongation factor, and can be synthetically manufactured.

'Structure'

It has 3 domains. G proteins, Elongation Factors, and the EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain. It is composed of 6 chains, which combine in alignment.

Specific are highlighted here.

which play a crucial role in binding to the ribosome during translation.

This is a 27 chain protein structure with 11244 amino acid alpha carbons. Like DNA polymerase, this complex is made up of multiple polypeptide chains with four different types of subunits, called α, β, β′, and σ. The σ subunit is relatively weak and can be separated leaving a core polymerase consisting of two α, one β, and one β′ subunits. The core polymerase can catalyze the polymerization of DNA into RNA by its self. The σ subunit is not required for the basic catalytic activity of the enzyme however, the core polymerase cannot bind to the proper DNA sequence and without it.

Function

The sigma factor, Rpod, binds to the RNA polymerase in place of the alpha subunit. This sigma factor allows the RNA polymerase to bind to the -35 and -10 consensus sequences so that the RNA polymerase active site is aligned with the start site. Once the RNA polymerase undergoes morphological changes, the RNA polymerase begins abortive transcription and the sigma factor can leave the complex. After this has been completed, transcription begins.

Location

Relevance

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.