Aminopeptidase

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Line 57: Line 57:
**[[4fys]] - hAla-AP + Zn + angiotensin<br />
**[[4fys]] - hAla-AP + Zn + angiotensin<br />
**[[4fyt]] - hAla-AP + Zn + amastatin<br />
**[[4fyt]] - hAla-AP + Zn + amastatin<br />
 +
 +
*Aminopeptidase N
 +
**[[3ked]] – EcAPN+2,4-diaminobutyric acid – ''Escherichia coli''<br />
**[[3ked]] – EcAPN+2,4-diaminobutyric acid – ''Escherichia coli''<br />
**[[2hpo]], [[2dq6]], [[3puu]] – EcAPN<br />
**[[2hpo]], [[2dq6]], [[3puu]] – EcAPN<br />
**[[2hpt]], [[2dqm]] – EcAPN+bestatin<br />
**[[2hpt]], [[2dqm]] – EcAPN+bestatin<br />
**[[2zxg]] – EcAPN+transition state analog<br />
**[[2zxg]] – EcAPN+transition state analog<br />
-
**[[3b2p]], [[3b2x]], [[3b34]], [[3b37]], [[3b3b]], [[3qjx]] – EcAPN+amino acid<br />
+
**[[3b2p]], [[3b2x]], [[3b34]], [[3b37]], [[3b3b]], [[3qjx]], [[4xo5]], [[4xo4]], [[4xo3]], [[4xnd]], [[4xnb]], [[4xna]], [[4xn9]], [[4xn8]], [[4xn7]], [[4xn5]], [[4xn4]], [[4xn2]], [[4xn1]], [[4xmz]], [[4xmx]], [[4xmw]], [[4xmv]], [[4xmu]], [[4xmt]] – EcAPN + Zn +amino acid<br />
-
**[[2gtq]] – NmAPN – ''Neisseria meningitides''
+
**[[4q4i]] – EcAPN+ Zn + peptide<br />
 +
**[[4q4e]] – EcAPN+ Zn + actinonin<br />
 +
**[[4ou3]] – pAPN+ Zn + peptide<br />
 +
**[[2gtq]] – NmAPN – ''Neisseria meningitides''<br />
 +
**[[5dyf]] – NmAPN + benzyl-diaminoethylphosphonate<br />
 +
**[[4pu2]], [[4pvb]] – NmAP N + Leu analog <br />
 +
**[[4pw4]] – NmAP N + Phe analog <br />
 +
**[[4qhp]], [[4qir]], [[4qme]], [[4qpe]], [[4quo]] – NmAP N + dipeptide analog <br />
 +
**[[5dll]] – FtAPN - ''Francisella tularensis''<br />
 +
**[[4fgm]] – AP N + Zn – ''Idiomarina loihiensis''<br />
*Proline aminopeptidase
*Proline aminopeptidase
Line 69: Line 81:
**[[3il0]] - Xaa Pro-AP – ''Streptococcus thermophilus''<br />
**[[3il0]] - Xaa Pro-AP – ''Streptococcus thermophilus''<br />
**[[2v3x]], [[2v3y]], [[2v3z]] - Xaa EcPro-AP (mutant)+tripeptide<br />
**[[2v3x]], [[2v3y]], [[2v3z]] - Xaa EcPro-AP (mutant)+tripeptide<br />
 +
**[[5cnx]] - Xaa EcPro-AP (mutant) + Zn<br />
**[[1w7v]], [[2bh3]] - Xaa EcPro-AP+Zn+Mg+polypeptide<br />
**[[1w7v]], [[2bh3]] - Xaa EcPro-AP+Zn+Mg+polypeptide<br />
**[[2bn7]] - Xaa EcPro-AP+Zn+Mg+Mn+polypeptide<br />
**[[2bn7]] - Xaa EcPro-AP+Zn+Mg+Mn+polypeptide<br />
Line 82: Line 95:
**[[1n51]] – Xaa EcPro-AP+apstatin<br />
**[[1n51]] – Xaa EcPro-AP+apstatin<br />
**[[3ig4]] - Xaa Pro-AP+ Mn – ''Bacillus anthracis''<br />
**[[3ig4]] - Xaa Pro-AP+ Mn – ''Bacillus anthracis''<br />
-
**[[4fkc]] – Xaa Pro-AP + Cd – ''Thermococcus sibiricus''<br />
+
**[[4fkc]] – Xaa TsPro-AP + Cd – ''Thermococcus sibiricus''<br />
 +
**[[4rgz]] – Xaa TsPro-AP + Zn<br />
**[[4pv4]] – Pro-AP II + Mg – ''Yersinia pestis''<br />
**[[4pv4]] – Pro-AP II + Mg – ''Yersinia pestis''<br />
**[[2zsg]] – X TmPro-AP – ''Thermatoga maritima''<br />
**[[2zsg]] – X TmPro-AP – ''Thermatoga maritima''<br />
Line 96: Line 110:
*Leucine aminopeptidase
*Leucine aminopeptidase
 +
**[[5jm9]], [[4r8f]] – yLeu-AP 1 - yeast <br />
 +
**[[5jhc]] – yLeu-AP 1 (mutant) <br />
 +
**[[5jgf]] – yLeu-AP 1 + Zn<br />
 +
**[[5jh9]] – yLeu-AP 1 (mutant) + Zn<br />
**[[3jru]] – Leu-AP – ''Xanthomonas oryzae''<br />
**[[3jru]] – Leu-AP – ''Xanthomonas oryzae''<br />
**[[2hc9]], [[2hb6]] – Leu-AP – ''Caenorhabditis elegans''<br />
**[[2hc9]], [[2hb6]] – Leu-AP – ''Caenorhabditis elegans''<br />
Line 104: Line 122:
**[[1lan]], [[1lcp]] – bLue-AP+leucine derivative<br />
**[[1lan]], [[1lcp]] – bLue-AP+leucine derivative<br />
**[[1bll]] – bLue-AP+amastatin<br />
**[[1bll]] – bLue-AP+amastatin<br />
-
**[[3rjo]] - hLeu-AP peptide-binding domain<br />
+
**[[3qnf]] – hLeu-AP 1<br />
-
**[[3mdj]] - hLeu-AP soluble domain + inhibitor<br />
+
**[[2xdt]], [[2yd0]] – hLeu-AP 1 soluble domain<br />
 +
**[[3rjo]] - hLeu-AP 1 peptide-binding domain<br />
 +
**[[3mdj]] - hLeu-AP 1 soluble domain + inhibitor<br />
**[[3h8e]], [[3h8f]], [[3h8g]] – Leu-AP – ''Pseudomonas putida''<br />
**[[3h8e]], [[3h8f]], [[3h8g]] – Leu-AP – ''Pseudomonas putida''<br />
**[[3kqx]], [[3kqz]], [[3kr4]], [[3kr5]] – PfLeu-AP <br />
**[[3kqx]], [[3kqz]], [[3kr4]], [[3kr5]] – PfLeu-AP <br />
Line 119: Line 139:
**[[1xry]], [[1txr]] – VpLeu-AP+bestatin<br />
**[[1xry]], [[1txr]] – VpLeu-AP+bestatin<br />
**[[1gyt]] – EcLeu-AP<br />
**[[1gyt]] – EcLeu-AP<br />
-
**[[3qnf]] – hLeu-AP 1<br />
 
**[[3t8w]], [[4k3n]], [[4r6t]] – PfLeu-AP + Zn + inhibitor <br />
**[[3t8w]], [[4k3n]], [[4r6t]] – PfLeu-AP + Zn + inhibitor <br />
-
**[[4r76]], [[4r7m]] – PfLeu-AP (mutant) + Zn + inhibitor <br />
+
**[[4r76]], [[4r7m]], [[4x2t]] – PfLeu-AP (mutant) + Zn + inhibitor <br />
**[[3tc8]] - PdLeu-AP + Zn<br />
**[[3tc8]] - PdLeu-AP + Zn<br />
**[[4fuu]] - Leu-AP + Zn – ''Bacterioides thetaiotaomicron''<br />
**[[4fuu]] - Leu-AP + Zn – ''Bacterioides thetaiotaomicron''<br />
-
**[[4ksi]] – Leu-AP + Mg – tomato<br />
+
**[[4ksi]] – toLeu-AP 1 + Mg – tomato<br />
 +
**[[5d8n]] – toLeu-AP 1 (mutant) + Mg <br />
 +
**[[5lhj]] – StrLeu-AP 2 – ''Streptomyces''<br />
 +
**[[5lhk]] – StrLeu-AP 2 + Mn <br />
 +
**[[4zla]], [[4zi6]] – Leu-AP + Zn – ''Helicobacter pylori'' <br />
*Leucine-cysteine aminopeptidase
*Leucine-cysteine aminopeptidase
-
**[[4p8q]] – hLeu-Cys-AP + Zn<br />
+
**[[4p8q]], [[5c97]] – hLeu-Cys-AP + Zn<br />
**[[4pj6]] – hLeu-Cys-AP + Zn + lysine<br />
**[[4pj6]] – hLeu-Cys-AP + Zn + lysine<br />
 +
**[[4z7i]] – hLeu-Cys-AP + Zn + peptide<br />
 +
 +
*Lysine aminopeptidase
 +
 +
**[[4x8i]] – PfLys-AP + Zn<br />
*Methionine aminopeptidase
*Methionine aminopeptidase
**[[3mr1]], [[3mx6]] – Met-AP+Mn – ''Rickettsia prowazekii''<br />
**[[3mr1]], [[3mx6]] – Met-AP+Mn – ''Rickettsia prowazekii''<br />
-
**[[2dfi]], [[1xgm]], [[1xgn]], [[1xgo]], [[1xgs]] – PfMet-AP+Co – ''Pyrococcus furiosus''<br />
+
**[[2dfi]], [[1xgm]], [[1xgn]], [[1xgo]], [[1xgs]] – PyfMet-AP+Co – ''Pyrococcus furiosus''<br />
-
**[[1wkm]] - PfMet-AP+Mn<br />
+
**[[1wkm]] - PyfMet-AP+Mn<br />
**[[4fo7]], [[4juq]] - PaMet-AP+Mn – ''Pseudomonas aeruginosa''<br />
**[[4fo7]], [[4juq]] - PaMet-AP+Mn – ''Pseudomonas aeruginosa''<br />
**[[4fo8]] - PaMet-AP+Mn + Met <br />
**[[4fo8]] - PaMet-AP+Mn + Met <br />
-
**[[4hxx]], [[4iu6]] - hMet-AP+ Co + pyrimidine derivative<br />
+
**[[4hxx]], [[4iu6]] - hMet-AP 1 + Co + pyrimidine derivative<br />
 +
**[[2nq6]], [[2nq7]], [[1yw7]], [[1yw8]], [[1yw9]] - hMet-AP 1 +Mn+inhibitor<br />
 +
**[[2b3h]], [[2b3k]] - hMet-AP 1 +Co<br />
 +
**[[2gz5]], [[4ikr]], [[4iks]], [[4ikt]], [[4iku]] – hMet-AP 1 +Co+inhibitor<br />
 +
**[[2g6p]] - hMet-AP 1 truncated+Mn+inhibitor<br />
 +
**[[2ea2]], [[2ea4]], [[2ga2]] - hMet-AP 2 +Mn+inhibitor<br />
 +
**[[1boa]] - hMet-AP 2 +Co+ angiogenesis inhibitor<br />
 +
**[[1kq0]], [[1kq9]] – hMet-AP 2 +methionine<br />
 +
**[[1qzy]], [[1b59]], [[1b6a]], [[1bn5]], [[2oaz]], [[5d6f]], [[5d6e]] - hMet-AP 2 +Co+inhibitor<br />
 +
**[[2adu]] - hMet-AP 2 (mutant) +Co+inhibitor<br />
 +
**[[1r58]], [[1r5g]], [[1r5h]] - hMet-AP 2 +Mn+inhibitor<br />
**[[3iu7]] – MtMet-AP+Mn +A02 – ''Mycobacterium tuberculosis''<br />
**[[3iu7]] – MtMet-AP+Mn +A02 – ''Mycobacterium tuberculosis''<br />
**[[3iu8]], [[3iu9]] - MtMet-AP+Ni + inhibitor<br />
**[[3iu8]], [[3iu9]] - MtMet-AP+Ni + inhibitor<br />
-
**[[1yj3]], [[3ror]] - MtMet-AP+Co<br />
+
**[[1yj3]], [[3ror]], [[4ook]] - MtMet-AP 2 +Co<br />
**[[3pka]] - MtMet-AP+Mn<br />
**[[3pka]] - MtMet-AP+Mn<br />
**[[3pkb]], [[3pkc]], [[3pkd]], [[3pke]] - MtMet-AP+bengamide inhibitor<br />
**[[3pkb]], [[3pkc]], [[3pkd]], [[3pke]] - MtMet-AP+bengamide inhibitor<br />
Line 155: Line 193:
**[[1c21]], [[1c22]], [[1c23]], [[1c24]] - EcMet-AP +Co + methionine derivative<br />
**[[1c21]], [[1c22]], [[1c23]], [[1c24]] - EcMet-AP +Co + methionine derivative<br />
**[[1c27]] - EcMet-AP +Co +norleucine<br />
**[[1c27]] - EcMet-AP +Co +norleucine<br />
-
**[[3tb5]] – Met-AP – ''Enterococcus faecalis''<br />
+
**[[3tb5]] – Met-AP – ''Enterococcus faecalis''<br />>
-
**[[2ea2]], [[2ea4]], [[2ga2]], [[2nq6]], [[2nq7]], [[1yw7]], [[1yw8]], [[1yw9]] - hMet-AP+Mn+inhibitor<br />
+
**[[2gtx]], [[2gu7]] – EcMet-AP<br />
**[[2gtx]], [[2gu7]] – EcMet-AP<br />
**[[1yvm]] – EcMet-AP (mutant)+Co+thiabendazole<br />
**[[1yvm]] – EcMet-AP (mutant)+Co+thiabendazole<br />
**[[1mat]] – EcMet-AP+Co<br />
**[[1mat]] – EcMet-AP+Co<br />
-
**[[2mat]], [[4mat]] - EcMet-AP (mutant)+Co<br />
+
**[[2mat]], [[4mat]], [[4u76]], [[4u75]], [[4u73]], [[4u71]], [[4u70]], [[4u6z]], [[4u6w]], [[4u6j]], [[4u6e]], [[4u6c]], [[4u769], [[4u1b]] - EcMet-AP 1 (mutant)+Co<br />
**[[3mat]] - EcMet-AP (mutant)+Co+bestatin derivative<br />
**[[3mat]] - EcMet-AP (mutant)+Co+bestatin derivative<br />
-
**[[2b3h]], [[2b3k]] - hMet-AP+Co<br />
+
**[[4fli]], [[4flj]], [[4flk]], [[4fll]] - hMet-AP 1 +Mn+inhibitor<br />
-
**[[1boa]] - hMet-AP+Co+ angiogenesis inhibitor<br />
+
-
**[[2b3l]] – hMet-AP<br />
+
-
**[[1kq0]], [[1kq9]] – hMet-AP+methionine<br />
+
-
**[[2gz5]], [[2adu]], [[1qzy]], [[1b59]], [[1b6a]], [[1bn5]], [[2oaz]], [[4ikr]], [[4iks]], [[4ikt]], [[4iku]] – hMet-AP+Co+inhibitor<br />
+
-
**[[1r58]], [[1r5g]], [[1r5h]], [[4fli]], [[4flj]], [[4flk]], [[4fll]] - hMet-AP+Mn+inhibitor<br />
+
-
**[[2g6p]] - hMet-AP truncated+Mn+inhibitor<br />
+
**[[1qxw]], [[1qxy]], [[1qxz]] – Met-AP+Co+inhibitor - ''Staphylococcus aureus''<br />
**[[1qxw]], [[1qxy]], [[1qxz]] – Met-AP+Co+inhibitor - ''Staphylococcus aureus''<br />
**[[1o0x]] – TmMet-AP<br />
**[[1o0x]] – TmMet-AP<br />
Line 177: Line 208:
*Arginine aminopeptidase
*Arginine aminopeptidase
-
**[[4jbs]] – hArg-AP+ Zn + inhibitor<br />
+
**[[5cu5]] – hArg-AP 2<br />
 +
**[[4jbs]] – hArg-AP 2 + Zn + inhibitor<br />
 +
**[[5ab2]], [[5ab0]] – hArg-AP 2 + Zn + peptide<br />
*Aspartic acid aminopeptidase
*Aspartic acid aminopeptidase
Line 197: Line 230:
*Cytosolic aminopeptidase
*Cytosolic aminopeptidase
-
**[[3pei]] – Cyt-AP – ''Francisella tularensis''<br />
+
**[[3pei]] – FtCyt-AP <br />
**[[3kzw]] – Cyt-AP – ''Staphylococcus aureus''<br />
**[[3kzw]] – Cyt-AP – ''Staphylococcus aureus''<br />
**[[3ij3]] – Cyt-AP – ''Coxiella burnetii''
**[[3ij3]] – Cyt-AP – ''Coxiella burnetii''
Line 225: Line 258:
**[[4pw4]] – NmAP N + Phe analog <br />
**[[4pw4]] – NmAP N + Phe analog <br />
**[[4qhp]], [[4qir]], [[4qme]], [[4qpe]], [[4quo]] – NmAP N + dipeptide analog <br />
**[[4qhp]], [[4qir]], [[4qme]], [[4qpe]], [[4quo]] – NmAP N + dipeptide analog <br />
 +
**[[4wwv]] – AP M42 – ''Desulfuroccus kamchatkensis''<br />
 +
**[[4p6y]] – TmAP M42 <br />
*Cold-activated aminopeptidase
*Cold-activated aminopeptidase
Line 262: Line 297:
**[[4j3b]] – PfAP (mutant)<br />
**[[4j3b]] – PfAP (mutant)<br />
**[[3t8v]] – PfAP M1<br />
**[[3t8v]] – PfAP M1<br />
-
**[[4k5l]], [[4k5m]], [[4k5n]], [[4k5p]], [[4k5o]] - PfLeu-AP (mutant) + Zn + inhibitor<br />
+
**[[4k5l]], [[4k5m]], [[4k5n]], [[4k5p]], [[4k5o]], [[5cbm]] - PfLeu-AP (mutant) + Zn + inhibitor<br />
 +
**[[4zx6]], [[4zx5]], [[4zx4]], [[4zx5]], [[4zx3]], [[4zw8]], [[4zw7]], [[4zw6]], [[4zw5]], [[4zw3]], [[4zqt]], [[4x2u]] - PfLeu-AP (mutant) + Zn + Mg + inhibitor<br />
*Aminopeptidase C
*Aminopeptidase C
**[[4k7c]] – AP – ''Lactobacillus rahmnosis''<br />
**[[4k7c]] – AP – ''Lactobacillus rahmnosis''<br />
 +
**[[5ib9]] – AP - ''Aneurinibacillus''<br />
*Tripeptidyl aminopeptidase see [[Tripeptidyl peptidase]]
*Tripeptidyl aminopeptidase see [[Tripeptidyl peptidase]]

Revision as of 11:32, 2 March 2017

Bacterial leucine aminopeptidase complex with 8-hydroxyquinoline, glycerol, SCN, Zn+2 (magenta), Na+ (cyan) and Cl- (green) ions (PDB code 3vh9)

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3D Structures of Aminopeptidase

Updated on 02-March-2017 {{#tree:id=OrganizedByTopic|openlevels=0|

  • Cysteine aminopeptidase
    • 3pw3 – PdCys-AP – Parabacteroides distasonis
  • Glutamic acid aminopeptidase
    • 2wyr – PhGlu-AP+Co – Pyrococcus horikoshii
    • 3kl9 – SpGlu-AP – Streptococcus pneumoniae
    • 4kx7 – hGlu-AP + Zn – human
    • 4kx8, 4kxb – hGlu-AP + Zn + statin derivative
    • 4kx9, 4kxa, 4kxc, 4kxd – hGlu-AP + Zn + amino acid
  • Alanine aminopeptidase
    • 3ebg – PfAla-AP - Plasmodium falciparum
    • 3ebh - PfAla-AP+bestatin
    • 3ebi - PfAla-AP+dipeptide analog
    • 4r5t, 4r5v, 4r5x – PfAla-AP + inhibitor
    • 4fke – pAla-AP + Zn – pig
    • 4fkh – pAla-AP + Zn + alanine
    • 4naq, 4nz8 – pAla-AP + Zn + polyalanine
    • 4hom – pAla-AP + Zn + substance P
    • 4fkk – pAla-AP + Zn + bestatin
    • 4f5c – pAla-AP + PRCV spike protein + Zn
    • 4fyq - hAla-AP + Zn
    • 4fyr - hAla-AP + Zn + bestatin
    • 4fys - hAla-AP + Zn + angiotensin
    • 4fyt - hAla-AP + Zn + amastatin
  • Aminopeptidase N
  • Proline aminopeptidase
    • 3ovk – Xaa Pro-AP – Streptococcus pyogenes
    • 3il0 - Xaa Pro-AP – Streptococcus thermophilus
    • 2v3x, 2v3y, 2v3z - Xaa EcPro-AP (mutant)+tripeptide
    • 5cnx - Xaa EcPro-AP (mutant) + Zn
    • 1w7v, 2bh3 - Xaa EcPro-AP+Zn+Mg+polypeptide
    • 2bn7 - Xaa EcPro-AP+Zn+Mg+Mn+polypeptide
    • 2bha, 2bhd - Xaa EcPro-AP+Mg+polypeptide
    • 1a16 - Xaa EcPro-AP+Mn+polypeptide
    • 1wbq, 2bhb - Xaa EcPro-AP+Zn+Mg
    • 2bhc - Xaa EcPro-AP+Na+Mg
    • 1wl6 - Xaa EcPro-AP+Mg
    • 1wl9, 1m35, 1jaw - Xaa EcPro-AP+Mn
    • 1wlr - Xaa EcPro-AP
    • 2bws, 2bwt, 2bwu, 2bwv, 2bww, 2bwx, 2bwy - Xaa EcPro-AP (mutant)
    • 1w2m - Xaa EcPro-AP+Ca
    • 1n51 – Xaa EcPro-AP+apstatin
    • 3ig4 - Xaa Pro-AP+ Mn – Bacillus anthracis
    • 4fkc – Xaa TsPro-AP + Cd – Thermococcus sibiricus
    • 4rgz – Xaa TsPro-AP + Zn
    • 4pv4 – Pro-AP II + Mg – Yersinia pestis
    • 2zsg – X TmPro-AP – Thermatoga maritima
    • 3ctz – X hPro-AP
    • 1x2b, 1x2e, 1wm1 – SmPro-AP + inhibitor – Serratia marcescens
    • 1qtr – SmPro-AP
    • 1xqv – TaPro-AP (mutant) – Thermoplasma acidophilum
    • 1xqw, 1xqx, 1xqy, 1xrl, 1xrm, 1xrn, 1xro, 1xrp, 1xrq, 1xrr – TaPro-AP+polypeptide
    • 3azo – SmPro-AP – Streptomyces morookaensis
    • 3azp - SmPro-AP (mutant)
    • 3azq - SmPro-AP (mutant) + PGG
  • Leucine aminopeptidase
    • 5jm9, 4r8f – yLeu-AP 1 - yeast
    • 5jhc – yLeu-AP 1 (mutant)
    • 5jgf – yLeu-AP 1 + Zn
    • 5jh9 – yLeu-AP 1 (mutant) + Zn
    • 3jru – Leu-AP – Xanthomonas oryzae
    • 2hc9, 2hb6 – Leu-AP – Caenorhabditis elegans
    • 2ewb – bLeu-AP+zofenoprilat – bovine
    • 1lam, 1lap – bLue-AP
    • 1bpm, 1bpn – bLue-AP+Zn+Mg
    • 2j9a - bLue-AP+Zn + inhibitor
    • 1lan, 1lcp – bLue-AP+leucine derivative
    • 1bll – bLue-AP+amastatin
    • 3qnf – hLeu-AP 1
    • 2xdt, 2yd0 – hLeu-AP 1 soluble domain
    • 3rjo - hLeu-AP 1 peptide-binding domain
    • 3mdj - hLeu-AP 1 soluble domain + inhibitor
    • 3h8e, 3h8f, 3h8g – Leu-AP – Pseudomonas putida
    • 3kqx, 3kqz, 3kr4, 3kr5 – PfLeu-AP
    • 3fh4, 1rtq, 2dea – VpLeu-AP – Vibrio proteolyticus
    • 3b35, 3b3t, 3b3v, 2anp - VpLeu-AP (mutant)
    • 3b3c, 3b3s, 3b3w - VpLeu-AP (mutant)+Leu derivative
    • 3b7i - VpLeu-AP (mutant)+Leu
    • 1ft7 - VpLeu-AP +Leu derivative
    • 3vh9 - VpLeu-AP + 8-quinolinol
    • 2nyq, 2iq6 – VpLeu-AP+polypeptide
    • 1lok – VpLeu-AP+Tris
    • 2prq – VpLeu-AP+Co
    • 1xry, 1txr – VpLeu-AP+bestatin
    • 1gyt – EcLeu-AP
    • 3t8w, 4k3n, 4r6t – PfLeu-AP + Zn + inhibitor
    • 4r76, 4r7m, 4x2t – PfLeu-AP (mutant) + Zn + inhibitor
    • 3tc8 - PdLeu-AP + Zn
    • 4fuu - Leu-AP + Zn – Bacterioides thetaiotaomicron
    • 4ksi – toLeu-AP 1 + Mg – tomato
    • 5d8n – toLeu-AP 1 (mutant) + Mg
    • 5lhj – StrLeu-AP 2 – Streptomyces
    • 5lhk – StrLeu-AP 2 + Mn
    • 4zla, 4zi6 – Leu-AP + Zn – Helicobacter pylori
  • Leucine-cysteine aminopeptidase
    • 4p8q, 5c97 – hLeu-Cys-AP + Zn
    • 4pj6 – hLeu-Cys-AP + Zn + lysine
    • 4z7i – hLeu-Cys-AP + Zn + peptide
  • Lysine aminopeptidase
    • 4x8i – PfLys-AP + Zn
  • Methionine aminopeptidase
  • Arginine aminopeptidase
    • 5cu5 – hArg-AP 2
    • 4jbs – hArg-AP 2 + Zn + inhibitor
    • 5ab2, 5ab0 – hArg-AP 2 + Zn + peptide
  • Aspartic acid aminopeptidase
    • 4dyo – hAsp-AP+aspartic hydroxamate
    • 3var, 3vat – bAsp-AP
    • 4eme – PfAsp-AP + Zn
  • Asparagine aminopeptidase
    • 3c17, 2zak – EcAsn-AP (mutant)
    • 2zal – EcAsn-AP+Asp
    • 2gez – Asn-AP – Lupinus luteus
  • Serine aminopeptidase
    • 1b65 – OaSer-AP – Ochrobactrum anthropi
  • Cytosolic aminopeptidase
    • 3pei – FtCyt-AP
    • 3kzw – Cyt-AP – Staphylococcus aureus
    • 3ij3 – Cyt-AP – Coxiella burnetii
  • Aminopeptidase 2
  • Non-specific aminopeptidase
    • 2ek8 – AnAP – Aneurinibacillus
    • 2ek9 – AnAP+bestatin
    • 1y0r, 1xfo – PhAP
    • 1y0y – PhAP+amastatin
    • 1amp - VpAP
    • 1cp6, 1igb – VpAP+inhibitor
    • 1ei5 – OaAP
    • 3edy, 3ee6 – hTripeptidyl-AP
    • 3zn8 – Dipeptidyl-AP B + signal recognition particle protein + signal recognition particle receptor + RNA – yeast
    • 4efd – TbAP M17 + Mn
    • 4fgm – AP N + Zn – Idiomarina loihiensis
    • 4icq – SpAP Peps + Zn
    • 4icr – SpAP Peps (mutant) + Zn
    • 4ics – SpAP Peps (mutant) + Zn + Trp + Gly
    • 4pu2, 4pvb – NmAP N + Leu analog
    • 4pw4 – NmAP N + Phe analog
    • 4qhp, 4qir, 4qme, 4qpe, 4quo – NmAP N + dipeptide analog
    • 4wwv – AP M42 – Desulfuroccus kamchatkensis
    • 4p6y – TmAP M42
  • Cold-activated aminopeptidase
    • 3cia – Col-AP – Colwellia psychrerythraea
  • Deblocking aminopeptidase
    • 2gre – DAP – Bacillus cereus
  • Heat stable aminopeptidase
    • 2ayi – AmpT – Thermus thermophilus
  • Aminopeptidase from Staphylococcus aureus
  • Metalloaminopeptidase
    • 3q43, 3q44 – PfPFAP (mutant) + bestatin derivative
  • Stereomyces griesus aminopeptidase
  • β-peptidyl aminopeptidase
    • 3n2w – SxBapA – Sphingosinicella xenopeptidilytica
    • 3n5i – SxBapA (mutant)
    • 3n33 – SxBapA + AEBSF
    • 3ndv, 3nfb – SxBapA + ampicillin
  • M1 family aminopeptidase
  • Aminopeptidase C
    • 4k7c – AP – Lactobacillus rahmnosis
    • 5ib9 – AP - Aneurinibacillus

}}

Additional Resources

For additional information, see:
Amino Acid Synthesis & Metabolism
Streptomyces griseus Aminopeptidase (SGAP)

References

  1. ↑ Taylor A. Aminopeptidases: structure and function. FASEB J. 1993 Feb 1;7(2):290-8. PMID:8440407
  2. ↑ Hanaya K, Suetsugu M, Saijo S, Yamato I, Aoki S. Potent inhibition of dinuclear zinc(II) peptidase, an aminopeptidase from Aeromonas proteolytica, by 8-quinolinol derivatives: inhibitor design based on Zn(2+) fluorophores, kinetic, and X-ray crystallographic study. J Biol Inorg Chem. 2012 Feb 5. PMID:22311113 doi:10.1007/s00775-012-0873-4

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