1sfo

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[[Image:1sfo.gif|left|200px]]
[[Image:1sfo.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1sfo |SIZE=350|CAPTION= <scene name='initialview01'>1sfo</scene>, resolution 3.61&Aring;
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The line below this paragraph, containing "STRUCTURE_1sfo", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1sfo| PDB=1sfo | SCENE= }}
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|RELATEDENTRY=[[1r9s|1R9S]], [[1r9t|1R9T]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sfo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sfo OCA], [http://www.ebi.ac.uk/pdbsum/1sfo PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1sfo RCSB]</span>
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}}
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'''RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX'''
'''RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX'''
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==About this Structure==
==About this Structure==
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1SFO is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry 1R9R. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFO OCA].
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1SFO is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1r9r 1r9r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFO OCA].
==Reference==
==Reference==
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[[Category: Kornberg, R D.]]
[[Category: Kornberg, R D.]]
[[Category: Westover, K D.]]
[[Category: Westover, K D.]]
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[[Category: dna]]
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[[Category: Dna]]
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[[Category: molecular machine]]
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[[Category: Molecular machine]]
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[[Category: mrna]]
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[[Category: Mrna]]
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[[Category: multiprotein complex]]
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[[Category: Multiprotein complex]]
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[[Category: transcription]]
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[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:38:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:41:25 2008''
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Revision as of 05:38, 3 May 2008

Image:1sfo.gif

Template:STRUCTURE 1sfo

RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX


Overview

The structure of an RNA polymerase II-transcribing complex has been determined in the posttranslocation state, with a vacancy at the growing end of the RNA-DNA hybrid helix. At the opposite end of the hybrid helix, the RNA separates from the template DNA. This separation of nucleic acid strands is brought about by interaction with a set of proteins loops in a strand/loop network. Formation of the network must occur in the transition from abortive initiation to promoter escape.

About this Structure

1SFO is a Protein complex structure of sequences from Saccharomyces cerevisiae. This structure supersedes the now removed PDB entry 1r9r. Full crystallographic information is available from OCA.

Reference

Structural basis of transcription: separation of RNA from DNA by RNA polymerase II., Westover KD, Bushnell DA, Kornberg RD, Science. 2004 Feb 13;303(5660):1014-6. PMID:14963331 Page seeded by OCA on Sat May 3 08:38:36 2008

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OCA

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