Sandbox Reserved 1226
From Proteopedia
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{{Sandbox_Reserved_Jason_Telford}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | {{Sandbox_Reserved_Jason_Telford}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
| - | == | + | ==Ubiquitin== |
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | ||
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
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| + | == Ubiquitin is a very small, very studied protein that is found in almost all cellular tissues in humans and other eukaryotic organisms. Ubiquitin consist of 76 amino acids. It helps regulate the processes of other proteins in the body. When ubiquitin is added to a substrate protein, the process of this occurring is known as ubiquitination. This process can lead to many different outcomes. Ubiquitination has three main steps: activation, conjugation and ligation which are performed by ubiquitin-activating enzymes, ubiquitin conjugating enzymes and ubiquitin ligase respectively. The main function of ubiquitin is degradation of the protein via the proteasome. Ubiquitin can affect many different processes including apoptosis, DNA transcription and repair, processing of antigens, viral infections, stress response pathway, immune and inflammatory responses, and degeneration of neurons and muscular cells. == | ||
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== Function == | == Function == | ||
Revision as of 20:52, 8 March 2017
| This Sandbox is Reserved from Jan 17 through June 31, 2017 for use in the course Biochemistry II taught by Jason Telford at the Maryville University, St. Louis, USA. This reservation includes Sandbox Reserved 1225 through Sandbox Reserved 1244. |
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Ubiquitin
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
