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5jnt
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human Low Molecular Weight Protein Tyrosine Phosphatase type A (LMPTP-A) complexed with MES== | |
| - | + | <StructureSection load='5jnt' size='340' side='right' caption='[[5jnt]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5jnt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JNT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jnr|5jnr]], [[5jns|5jns]], [[5jnu|5jnu]], [[5jnv|5jnv]], [[5jnw|5jnw]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jnt OCA], [http://pdbe.org/5jnt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jnt RCSB], [http://www.ebi.ac.uk/pdbsum/5jnt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jnt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PPAC_HUMAN PPAC_HUMAN]] Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Protein-tyrosine-phosphatase]] | ||
| + | [[Category: Aleshin, A E]] | ||
| + | [[Category: Bankston, L]] | ||
| + | [[Category: Bottini, N]] | ||
[[Category: Cadwell, G]] | [[Category: Cadwell, G]] | ||
| - | [[Category: | + | [[Category: Liddington, R C]] |
| - | [[Category: | + | [[Category: Stanford, S M]] |
| + | [[Category: Diabetes]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Lmptp]] | ||
| + | [[Category: Lmptp-a]] | ||
| + | [[Category: Lmw-ptp]] | ||
| + | [[Category: Tyrosine phosphatase]] | ||
Revision as of 13:45, 29 March 2017
Crystal Structure of human Low Molecular Weight Protein Tyrosine Phosphatase type A (LMPTP-A) complexed with MES
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