5mec

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'''Unreleased structure'''
 
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The entry 5mec is ON HOLD until Paper Publication
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==Crystal structure of yeast Cdt1 middle domain (residues 294-433)==
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<StructureSection load='5mec' size='340' side='right' caption='[[5mec]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
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Authors: Pye, V.E., Frigola, J., Diffley, J.F.X., Cherepanov, P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5mec]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MEC FirstGlance]. <br>
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Description: Crystal structure of yeast Cdt1 middle domain (residues 294-433)
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mec OCA], [http://pdbe.org/5mec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mec RCSB], [http://www.ebi.ac.uk/pdbsum/5mec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mec ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Pye, V.E]]
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== Function ==
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[[http://www.uniprot.org/uniprot/CDT1_YEAST CDT1_YEAST]] DNA replication licensing factor, required for pre-replication complex assembly. Faithful duplication of the genetic material requires 'once per cell cycle' DNA replication initiation and elongation. Central to this control is the tightly regulated formation of prereplicative complexes (preRCs) at future origins of DNA replication. Required for the recruitment of the MCM2-7 helicase complex to the replication origins.<ref>PMID:11560884</ref> <ref>PMID:11967159</ref> <ref>PMID:16387651</ref> <ref>PMID:16824194</ref> <ref>PMID:17825064</ref> <ref>PMID:18006685</ref> <ref>PMID:19896182</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Cherepanov, P]]
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[[Category: Diffley, J F.X]]
[[Category: Frigola, J]]
[[Category: Frigola, J]]
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[[Category: Diffley, J.F.X]]
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[[Category: Pye, V E]]
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[[Category: Cherepanov, P]]
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[[Category: Cdt1]]
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[[Category: Cell cycle]]
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[[Category: Dna replication]]
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[[Category: Mcm]]
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[[Category: Winged helix]]
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[[Category: Yeast]]

Revision as of 15:48, 17 May 2017

Crystal structure of yeast Cdt1 middle domain (residues 294-433)

5mec, resolution 2.13Å

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