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5mzn

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m (Protected "5mzn" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5mzn is ON HOLD until Paper Publication
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==Helicase Sen1==
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<StructureSection load='5mzn' size='340' side='right' caption='[[5mzn]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
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Authors: Leonaite, B., Basquin, J., Conti, E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5mzn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MZN FirstGlance]. <br>
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Description: Helicase Sen1
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mzn OCA], [http://pdbe.org/5mzn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mzn RCSB], [http://www.ebi.ac.uk/pdbsum/5mzn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mzn ProSAT]</span></td></tr>
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[[Category: Leonaite, B]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SEN1_YEAST SEN1_YEAST]] ATP-dependent 5'->3' DNA/RNA helicase required for the expression and maturation of diverse classes of non-protein-coding RNAs like precursor tRNAs, rRNAs and small nuclear (snRNA) and nucleolar (snoRNA) RNAs. Directs RNA polymerase II transcription termination on snoRNAs as well as on several short protein-coding genes. May also play a role in transcription-coupled nucleotide excision repair.<ref>PMID:11565036</ref> <ref>PMID:15121901</ref> <ref>PMID:17157256</ref> <ref>PMID:8943355</ref> <ref>PMID:9365256</ref> <ref>PMID:9819377</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Basquin, J]]
[[Category: Basquin, J]]
[[Category: Conti, E]]
[[Category: Conti, E]]
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[[Category: Leonaite, B]]
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[[Category: Hydrolase]]
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[[Category: Yeast helicase domain sen1]]

Revision as of 13:01, 19 April 2017

Helicase Sen1

5mzn, resolution 1.79Å

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