5n8v
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.== | |
| - | + | <StructureSection load='5n8v' size='340' side='right' caption='[[5n8v]], [[Resolution|resolution]] 1.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5n8v]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N8V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KZZ:1-(2-AZANYLETHYL)-5-[(4-METHOXYNAPHTHALEN-1-YL)METHYL]-~{N}-(NAPHTHALEN-1-YLMETHYL)-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE'>KZZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5l8a|5l8a]], [[5l87|5l87]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n8v OCA], [http://pdbe.org/5n8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n8v RCSB], [http://www.ebi.ac.uk/pdbsum/5n8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n8v ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Dawidowski, M]] | [[Category: Dawidowski, M]] | ||
| - | [[Category: Popowicz, G.M]] | ||
[[Category: Emmanouilidis, L]] | [[Category: Emmanouilidis, L]] | ||
| + | [[Category: Popowicz, G M]] | ||
[[Category: Sattler, M]] | [[Category: Sattler, M]] | ||
| + | [[Category: Glycosome]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Protein-protein interaction inhibitor]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Structure-based drug discovery]] | ||
| + | [[Category: Trypanosomiasis]] | ||
Revision as of 21:21, 15 March 2017
Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
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