1gws
From Proteopedia
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| - | [[Image:1gws.gif|left|200px]]<br /> | + | [[Image:1gws.gif|left|200px]]<br /><applet load="1gws" size="450" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1gws" size="450" color="white" frame="true" align="right" spinBox="true" | + | |
caption="1gws, resolution 2.40Å" /> | caption="1gws, resolution 2.40Å" /> | ||
'''HEXADECAHEME HIGH MOLECULAR WEIGHT CYTOCHROME HMC FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH'''<br /> | '''HEXADECAHEME HIGH MOLECULAR WEIGHT CYTOCHROME HMC FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1GWS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris] with HEM and HEC as [http://en.wikipedia.org/wiki/ligands ligands]. | + | 1GWS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris] with HEM and HEC as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:Hec Binding Site For Residue A 616'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWS OCA]. |
==Reference== | ==Reference== | ||
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[[Category: sulfate reducing bacteria]] | [[Category: sulfate reducing bacteria]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 15:43:05 2007'' |
Revision as of 13:33, 18 December 2007
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HEXADECAHEME HIGH MOLECULAR WEIGHT CYTOCHROME HMC FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH
Overview
Sulfate-reducing bacteria contain a variety of multi-heme c-type, cytochromes. The cytochrome of highest molecular weight (Hmc) contains 16, heme groups and is part of a transmembrane complex involved in the sulfate, respiration pathway. We present the 2.42 A resolution crystal structure of, the Desulfovibrio vulgaris Hildenborough cytochrome Hmc and a structural, model of the complex with its physiological electron transfer partner, cytochrome c(3), obtained by NMR restrained soft-docking calculations. The, Hmc is composed of three domains, which exist independently in different, sulfate-reducing species, namely cytochrome c(3), cytochrome c(7), and, Hcc. The complex involves the last heme at the C-terminal region of the, V-shaped Hmc and heme 4 of cytochrome c(3), and represents an example for, specific cytochrome-cytochrome interaction.
About this Structure
1GWS is a Single protein structure of sequence from Desulfovibrio vulgaris with HEM and HEC as ligands. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
The crystal structure of the hexadeca-heme cytochrome Hmc and a structural model of its complex with cytochrome c(3)., Czjzek M, ElAntak L, Zamboni V, Morelli X, Dolla A, Guerlesquin F, Bruschi M, Structure. 2002 Dec;10(12):1677-86. PMID:12467575
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