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5t4k

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'''Unreleased structure'''
 
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The entry 5t4k is ON HOLD until Paper Publication
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==PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation==
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<StructureSection load='5t4k' size='340' side='right' caption='[[5t4k]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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Authors: Wu, R., Sanishvili, R., Belitsky, B.R., Juncosa, J.I., Le, H.V., Lehrer, H.J.S., Farley, M., Silverman, R.B., Petsko, G.A., Ringe, D., Liu, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5t4k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T4K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T4K FirstGlance]. <br>
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Description: PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=76U:(4S)-5-FLUORO-4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]PENTANOIC+ACID'>76U</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t4l|5t4l]]</td></tr>
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[[Category: Belitsky, B.R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t4k OCA], [http://pdbe.org/5t4k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t4k RCSB], [http://www.ebi.ac.uk/pdbsum/5t4k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t4k ProSAT]</span></td></tr>
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[[Category: Sanishvili, R]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GABR_BACSU GABR_BACSU]] Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate.<ref>PMID:12123465</ref> <ref>PMID:15223311</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Belitsky, B R]]
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[[Category: Farley, M]]
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[[Category: Juncosa, J I]]
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[[Category: Le, H V]]
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[[Category: Lehrer, H J.S]]
[[Category: Liu, D]]
[[Category: Liu, D]]
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[[Category: Juncosa, J.I]]
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[[Category: Petsko, G A]]
[[Category: Ringe, D]]
[[Category: Ringe, D]]
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[[Category: Sanishvili, R]]
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[[Category: Silverman, R B]]
[[Category: Wu, R]]
[[Category: Wu, R]]
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[[Category: Petsko, G.A]]
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[[Category: External aldimine]]
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[[Category: Silverman, R.B]]
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[[Category: Gaba]]
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[[Category: Farley, M]]
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[[Category: Gabr]]
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[[Category: Le, H.V]]
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[[Category: Mocr]]
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[[Category: Lehrer, H.J.S]]
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[[Category: Plp]]
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[[Category: Transcription]]

Revision as of 14:04, 29 March 2017

PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation

5t4k, resolution 2.25Å

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