5ues
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==BRD4_BD2_A-1344772== | |
| - | + | <StructureSection load='5ues' size='340' side='right' caption='[[5ues]], [[Resolution|resolution]] 1.62Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ues]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UES OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UES FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=87S:5-[2-(4-chlorophenoxy)phenyl]-2-methyl-1H-pyrrole-3-carboxamide'>87S</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uf0|5uf0]], [[5uez|5uez]], [[5uey|5uey]], [[5uex|5uex]], [[5uev|5uev]], [[5uep|5uep]], [[5uet|5uet]], [[5uer|5uer]], [[5ueq|5ueq]], [[5ueu|5ueu]], [[5ueo|5ueo]], [[5uew|5uew]]</td></tr> |
| - | [[Category: Park, C | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ues FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ues OCA], [http://pdbe.org/5ues PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ues RCSB], [http://www.ebi.ac.uk/pdbsum/5ues PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ues ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Park, C H]] | ||
| + | [[Category: Signaling protein-inhibitor complex]] | ||
Revision as of 11:16, 6 November 2017
BRD4_BD2_A-1344772
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