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5uie

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'''Unreleased structure'''
 
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The entry 5uie is ON HOLD until Paper Publication
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==Vps4-Vta1 complex==
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<StructureSection load='5uie' size='340' side='right' caption='[[5uie]], [[Resolution|resolution]] 5.70&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5uie]] is a 19 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UIE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UIE FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uie OCA], [http://pdbe.org/5uie PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uie RCSB], [http://www.ebi.ac.uk/pdbsum/5uie PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uie ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/VPS4_YEAST VPS4_YEAST]] Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex.<ref>PMID:11329380</ref> <ref>PMID:9155008</ref> <ref>PMID:9606181</ref> [[http://www.uniprot.org/uniprot/VTA1_YEAST VTA1_YEAST]] Has a role in the formation of the multivesicular body (MVB). Required for the sorting of lipids to form intralumenal vesicles and for fluid-phase transport to the vacuole. Required for sorting the plasma membrane proteins STE2 and STE3 into the MVB. Acts a cofactor of VSP4, promotes the oligomerization of VPS4 and stimulates its ATPase activity by 6- to 8-fold.<ref>PMID:12953057</ref> <ref>PMID:14701806</ref> <ref>PMID:16505166</ref> <ref>PMID:16601096</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Han, H]]
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[[Category: Hill, C P]]
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[[Category: Monroe, N]]
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[[Category: Shen, P]]
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[[Category: Sundquist, W I]]
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[[Category: Aaa atpase]]
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[[Category: Escrt]]
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[[Category: Transport protein]]
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[[Category: Vps4]]
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[[Category: Vta1]]

Revision as of 11:48, 12 April 2017

Vps4-Vta1 complex

5uie, resolution 5.70Å

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