5uke
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR structure of monomeric human IRAK-M Death Domain R56D, Y61E mutant== | |
| - | + | <StructureSection load='5uke' size='340' side='right' caption='[[5uke]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5uke]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UKE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UKE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uke OCA], [http://pdbe.org/5uke PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uke RCSB], [http://www.ebi.ac.uk/pdbsum/5uke PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uke ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/IRAK3_HUMAN IRAK3_HUMAN]] Disease susceptibility is associated with variations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IRAK3_HUMAN IRAK3_HUMAN]] Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.[UniProtKB:Q8K4B2]<ref>PMID:10383454</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Kwon, J]] | ||
| + | [[Category: Nicholson, L K]] | ||
| + | [[Category: Asthma]] | ||
| + | [[Category: Death domain]] | ||
| + | [[Category: Innate immunity]] | ||
| + | [[Category: Irak-m]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 18:24, 24 January 2018
NMR structure of monomeric human IRAK-M Death Domain R56D, Y61E mutant
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