5uti

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m (Protected "5uti" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5uti is ON HOLD until Paper Publication
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==Crystal Structure of TGT in complex with fragment in preQ1 pocket==
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<StructureSection load='5uti' size='340' side='right' caption='[[5uti]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5uti]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UTI FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GGB:L-CANAVANINE'>GGB</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA-guanine(34)_transglycosylase tRNA-guanine(34) transglycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uti OCA], [http://pdbe.org/5uti PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uti RCSB], [http://www.ebi.ac.uk/pdbsum/5uti PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uti ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
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__TOC__
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</StructureSection>
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[[Category: Hassaan, E]]
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[[Category: Heine, A]]
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[[Category: Klebe, G]]
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[[Category: Guanine exchange enzyme]]
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[[Category: Guanine pocket]]
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[[Category: Preq1 pocket]]
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[[Category: Tgt]]
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[[Category: Transferase]]
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[[Category: Trna]]

Revision as of 05:00, 8 March 2018

Crystal Structure of TGT in complex with fragment in preQ1 pocket

5uti, resolution 1.36Å

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