5x3v
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human SHMT2 protein mutant== | |
| - | + | <StructureSection load='5x3v' size='340' side='right' caption='[[5x3v]], [[Resolution|resolution]] 2.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5x3v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X3V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x3v OCA], [http://pdbe.org/5x3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x3v RCSB], [http://www.ebi.ac.uk/pdbsum/5x3v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x3v ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Glycine hydroxymethyltransferase]] | ||
| + | [[Category: Li, J]] | ||
| + | [[Category: Sheng, J]] | ||
| + | [[Category: Serine hydroxymethyltransferase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:29, 15 February 2018
Structure of human SHMT2 protein mutant
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