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5iaw

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==Novel natural FXR modulator with a unique binding mode==
==Novel natural FXR modulator with a unique binding mode==
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<StructureSection load='5iaw' size='340' side='right' caption='[[5iaw]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
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<StructureSection load='5iaw' size='340' side='right'caption='[[5iaw]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5iaw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IAW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IAW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5iaw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IAW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IAW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T73:(1S,2R,4S)-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-YL+4-HYDROXYBENZOATE'>T73</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=T73:(1S,2R,4S)-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-YL+4-HYDROXYBENZOATE'>T73</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iaw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iaw OCA], [http://pdbe.org/5iaw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iaw RCSB], [http://www.ebi.ac.uk/pdbsum/5iaw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iaw ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1H4, BAR, FXR, HRR1, RIP14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5iaw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iaw OCA], [http://pdbe.org/5iaw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iaw RCSB], [http://www.ebi.ac.uk/pdbsum/5iaw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iaw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Li, Y]]
[[Category: Li, Y]]
[[Category: Lu, Y]]
[[Category: Lu, Y]]
[[Category: Nuclear protein receptor]]
[[Category: Nuclear protein receptor]]
[[Category: Transcription]]
[[Category: Transcription]]

Revision as of 07:10, 3 June 2020

Novel natural FXR modulator with a unique binding mode

PDB ID 5iaw

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