This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4yd0
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Influenza polymerase basic protein 2 (PB2) bound to an azaindole-tetrazole inhibitor== | ==Influenza polymerase basic protein 2 (PB2) bound to an azaindole-tetrazole inhibitor== | ||
| - | <StructureSection load='4yd0' size='340' side='right' caption='[[4yd0]], [[Resolution|resolution]] 2.62Å' scene=''> | + | <StructureSection load='4yd0' size='340' side='right'caption='[[4yd0]], [[Resolution|resolution]] 2.62Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4yd0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YD0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YD0 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4yd0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/I75a0 I75a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YD0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YD0 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4EW:2-(5-CHLORO-1H-PYRROLO[2,3-B]PYRIDIN-3-YL)-5-FLUORO-N-[(1R,2S,3S,4R)-3-(1H-TETRAZOL-5-YL)BICYCLO[2.2.2]OCT-2-YL]PYRIMIDIN-4-AMINE'>4EW</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4EW:2-(5-CHLORO-1H-PYRROLO[2,3-B]PYRIDIN-3-YL)-5-FLUORO-N-[(1R,2S,3S,4R)-3-(1H-TETRAZOL-5-YL)BICYCLO[2.2.2]OCT-2-YL]PYRIMIDIN-4-AMINE'>4EW</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PB2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=383596 I75A0])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yd0 OCA], [http://pdbe.org/4yd0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yd0 RCSB], [http://www.ebi.ac.uk/pdbsum/4yd0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yd0 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yd0 OCA], [http://pdbe.org/4yd0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yd0 RCSB], [http://www.ebi.ac.uk/pdbsum/4yd0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yd0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 18: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 4yd0" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4yd0" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: I75a0]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Jacobs, M D]] | [[Category: Jacobs, M D]] | ||
[[Category: Flu]] | [[Category: Flu]] | ||
| Line 27: | Line 33: | ||
[[Category: M7-gtp pocket]] | [[Category: M7-gtp pocket]] | ||
[[Category: Small-molecule drug]] | [[Category: Small-molecule drug]] | ||
| + | [[Category: Transcription-inhibitor complex]] | ||
Revision as of 07:12, 12 June 2019
Influenza polymerase basic protein 2 (PB2) bound to an azaindole-tetrazole inhibitor
| |||||||||||
