This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4q7b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Human Aldose Reductase complexed with a ligand with an IDD structure ([2-(benzylcarbamoyl)-5-fluorophenoxy]acetic acid) at 1.19 A==
==Human Aldose Reductase complexed with a ligand with an IDD structure ([2-(benzylcarbamoyl)-5-fluorophenoxy]acetic acid) at 1.19 A==
-
<StructureSection load='4q7b' size='340' side='right' caption='[[4q7b]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
+
<StructureSection load='4q7b' size='340' side='right'caption='[[4q7b]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4q7b]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q7B FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4q7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q7B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YZ:[2-(BENZYLCARBAMOYL)-5-FLUOROPHENOXY]ACETIC+ACID'>2YZ</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YZ:[2-(BENZYLCARBAMOYL)-5-FLUOROPHENOXY]ACETIC+ACID'>2YZ</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1us0|1us0]], [[2ikj|2ikj]], [[4puu|4puu]], [[4puw|4puw]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1us0|1us0]], [[2ikj|2ikj]], [[4puu|4puu]], [[4puw|4puw]]</td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q7b OCA], [http://pdbe.org/4q7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q7b RCSB], [http://www.ebi.ac.uk/pdbsum/4q7b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q7b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q7b OCA], [http://pdbe.org/4q7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q7b RCSB], [http://www.ebi.ac.uk/pdbsum/4q7b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q7b ProSAT]</span></td></tr>
Line 13: Line 14:
==See Also==
==See Also==
-
*[[Aldose Reductase|Aldose Reductase]]
+
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aldehyde reductase]]
[[Category: Aldehyde reductase]]
 +
[[Category: Human]]
 +
[[Category: Large Structures]]
[[Category: Heine, A]]
[[Category: Heine, A]]
[[Category: Klebe, G]]
[[Category: Klebe, G]]

Revision as of 09:11, 24 April 2019

Human Aldose Reductase complexed with a ligand with an IDD structure ([2-(benzylcarbamoyl)-5-fluorophenoxy]acetic acid) at 1.19 A

PDB ID 4q7b

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools