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4xve
From Proteopedia
(Difference between revisions)
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==17beta-HSD5 in complex with 3-pentyl-2-[(pyridin-2-ylmethyl)sulfanyl]-7-(pyrrolidin-1-ylcarbonyl)quinazolin-4(3H)-one== | ==17beta-HSD5 in complex with 3-pentyl-2-[(pyridin-2-ylmethyl)sulfanyl]-7-(pyrrolidin-1-ylcarbonyl)quinazolin-4(3H)-one== | ||
| - | <StructureSection load='4xve' size='340' side='right' caption='[[4xve]], [[Resolution|resolution]] 1.55Å' scene=''> | + | <StructureSection load='4xve' size='340' side='right'caption='[[4xve]], [[Resolution|resolution]] 1.55Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4xve]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XVE FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4xve]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XVE FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=WDS:3-PENTYL-2-[(PYRIDIN-2-YLMETHYL)SULFANYL]-7-(PYRROLIDIN-1-YLCARBONYL)QUINAZOLIN-4(3H)-ONE'>WDS</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=WDS:3-PENTYL-2-[(PYRIDIN-2-YLMETHYL)SULFANYL]-7-(PYRROLIDIN-1-YLCARBONYL)QUINAZOLIN-4(3H)-ONE'>WDS</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wdt|4wdt]], [[4wdu|4wdu]], [[4wdw|4wdw]], [[4wdx|4wdx]], [[4xvd|4xvd]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wdt|4wdt]], [[4wdu|4wdu]], [[4wdw|4wdw]], [[4wdx|4wdx]], [[4xvd|4xvd]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1C3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Testosterone_17-beta-dehydrogenase_(NADP(+)) Testosterone 17-beta-dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.64 1.1.1.64] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Testosterone_17-beta-dehydrogenase_(NADP(+)) Testosterone 17-beta-dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.64 1.1.1.64] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xve OCA], [http://pdbe.org/4xve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xve RCSB], [http://www.ebi.ac.uk/pdbsum/4xve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xve ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xve OCA], [http://pdbe.org/4xve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xve RCSB], [http://www.ebi.ac.uk/pdbsum/4xve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xve ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Amano, Y]] | [[Category: Amano, Y]] | ||
[[Category: Yamaguchi, T]] | [[Category: Yamaguchi, T]] | ||
[[Category: Aldo-keto reductase inhibitor]] | [[Category: Aldo-keto reductase inhibitor]] | ||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
Revision as of 23:24, 5 June 2019
17beta-HSD5 in complex with 3-pentyl-2-[(pyridin-2-ylmethyl)sulfanyl]-7-(pyrrolidin-1-ylcarbonyl)quinazolin-4(3H)-one
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