1tf3

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[[Image:1tf3.gif|left|200px]]
[[Image:1tf3.gif|left|200px]]
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{{Structure
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|PDB= 1tf3 |SIZE=350|CAPTION= <scene name='initialview01'>1tf3</scene>
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The line below this paragraph, containing "STRUCTURE_1tf3", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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|ACTIVITY=
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|GENE=
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{{STRUCTURE_1tf3| PDB=1tf3 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tf3 OCA], [http://www.ebi.ac.uk/pdbsum/1tf3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tf3 RCSB]</span>
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'''TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES'''
'''TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES'''
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[[Category: Wuttke, D S.]]
[[Category: Wuttke, D S.]]
[[Category: 5s rna gene]]
[[Category: 5s rna gene]]
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[[Category: complex (transcription regulation/dna)]]
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[[Category: Dna]]
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[[Category: dna]]
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[[Category: Dna binding protein]]
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[[Category: dna binding protein]]
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[[Category: Nmr]]
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[[Category: nmr]]
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[[Category: Protein]]
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[[Category: protein]]
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[[Category: Tfiiia]]
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[[Category: tfiiia]]
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[[Category: Transcription factor]]
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[[Category: transcription factor]]
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[[Category: Zinc finger]]
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[[Category: zinc finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:52:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:55:09 2008''
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Revision as of 06:52, 3 May 2008

Image:1tf3.gif

Template:STRUCTURE 1tf3

TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES


Overview

The three N-terminal zinc fingers of transcription factor IIIA bind in the DNA major groove. Substantial packing interfaces are formed between adjacent fingers, the linkers lose their intrinsic flexibility upon DNA binding, and several lysine side chains implicated in DNA recognition are dynamically disordered.

About this Structure

1TF3 is a Single protein structure of sequence from Xenopus laevis. Full crystallographic information is available from OCA.

Reference

Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA., Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE, Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:9253405 Page seeded by OCA on Sat May 3 09:52:35 2008

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OCA

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