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5tl9
From Proteopedia
(Difference between revisions)
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==crystal structure of mPGES-1 bound to inhibitor== | ==crystal structure of mPGES-1 bound to inhibitor== | ||
| - | <StructureSection load='5tl9' size='340' side='right' caption='[[5tl9]], [[Resolution|resolution]] 1.20Å' scene=''> | + | <StructureSection load='5tl9' size='340' side='right'caption='[[5tl9]], [[Resolution|resolution]] 1.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5tl9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TL9 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5tl9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TL9 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7DN:2-{2-[(1S,2S)-2-{[1-(8-METHYLQUINOLIN-2-YL)PIPERIDINE-4-CARBONYL]AMINO}CYCLOPENTYL]ETHYL}BENZOIC+ACID'>7DN</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=JZR:HEXYL+BETA-D-GLUCOPYRANOSIDE'>JZR</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7DN:2-{2-[(1S,2S)-2-{[1-(8-METHYLQUINOLIN-2-YL)PIPERIDINE-4-CARBONYL]AMINO}CYCLOPENTYL]ETHYL}BENZOIC+ACID'>7DN</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=JZR:HEXYL+BETA-D-GLUCOPYRANOSIDE'>JZR</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTGES, MGST1L1, MPGES1, PGES, PIG12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tl9 OCA], [http://pdbe.org/5tl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tl9 RCSB], [http://www.ebi.ac.uk/pdbsum/5tl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tl9 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tl9 OCA], [http://pdbe.org/5tl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tl9 RCSB], [http://www.ebi.ac.uk/pdbsum/5tl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tl9 ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5tl9" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5tl9" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Prostaglandin E synthase|Prostaglandin E synthase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Prostaglandin-E synthase]] | [[Category: Prostaglandin-E synthase]] | ||
[[Category: Antonysamy, S]] | [[Category: Antonysamy, S]] | ||
Revision as of 09:24, 4 December 2019
crystal structure of mPGES-1 bound to inhibitor
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