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Sandbox Reserved 1063

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<Structure load='3TGN' size='350' frame='true' align='right' caption='3TGN' scene='Insert optional scene name here' />
<Structure load='3TGN' size='350' frame='true' align='right' caption='3TGN' scene='Insert optional scene name here' />
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Zinc-Dependent Transcriptional Regulator AdcR has <scene name='69/694230/Binding_site_space_fill/1'>two binding sites</scene> on each of its two domains (important amino acids for zinc binding shown in white).
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Zinc-Dependent Transcriptional Regulator AdcR has <scene name='69/694230/Binding_site_space_fill/1'>two binding sites</scene> on each of its two domains (important amino acids for zinc binding shown in white) and can bind a total of four zinc ions at one time. Of the two binding sites, binding site 1 is the only site with known importance for DNA binding. The function of binding site 2 is unknown.
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+
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<scene name='69/694230/Zoomed_in_space_fill_binding/1'>Zoomed in Binding Site</scene>
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=== Binding Site 1 ===
=== Binding Site 1 ===
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<scene name='69/694230/Binding_site_1/1'>binding site 1</scene>
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<scene name='69/694230/Binding_site_1/1'>Binding site 1</scene> consists of a distorted tetrahedral geometry around the zinc ion. The four amino acids involved are E24, H42, H108, and H112.
=== Binding Site 2 ===
=== Binding Site 2 ===
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<scene name='69/694230/Binding_site_2/1'>binding site 2</scene>
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<scene name='69/694230/Binding_site_2/1'>Binding site 2</scene> consists of a highly distorted tetrahedral geometry around the zinc ion. There are three amino acids involved in the binding of the zinc ion (C30, E41, and E107) as well as a water molecule.
== Mechanism of Action ==
== Mechanism of Action ==

Revision as of 12:38, 14 March 2017

This Sandbox is Reserved from 02/09/2015, through 05/31/2016 for use in the course "CH462: Biochemistry 2" taught by Geoffrey C. Hoops at the Butler University. This reservation includes Sandbox Reserved 1051 through Sandbox Reserved 1080.
To get started:
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  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
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More help: Help:Editing

Contents

3TGN

Zinc-Dependent MarR Family Transcriptional Regulator AdcR

Figure Legend
Figure Legend

Write general information about protein here

3TGN

Drag the structure with the mouse to rotate

Zinc-Dependent Transcriptional Regulator AdcR has on each of its two domains (important amino acids for zinc binding shown in white) and can bind a total of four zinc ions at one time. Of the two binding sites, binding site 1 is the only site with known importance for DNA binding. The function of binding site 2 is unknown.

Binding Site 1

consists of a distorted tetrahedral geometry around the zinc ion. The four amino acids involved are E24, H42, H108, and H112.

Binding Site 2

consists of a highly distorted tetrahedral geometry around the zinc ion. There are three amino acids involved in the binding of the zinc ion (C30, E41, and E107) as well as a water molecule.

Mechanism of Action

Zinc Ligand(s)

Other Ligands

DNA Binding

DNA Binding occurs in the

</StructureSection>

References

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