1ti8

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[[Image:1ti8.gif|left|200px]]
[[Image:1ti8.gif|left|200px]]
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{{Structure
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|PDB= 1ti8 |SIZE=350|CAPTION= <scene name='initialview01'>1ti8</scene>, resolution 3.00&Aring;
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The line below this paragraph, containing "STRUCTURE_1ti8", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1ti8| PDB=1ti8 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ti8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ti8 OCA], [http://www.ebi.ac.uk/pdbsum/1ti8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ti8 RCSB]</span>
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}}
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'''H7 Haemagglutinin'''
'''H7 Haemagglutinin'''
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[[Category: Stevens, D J.]]
[[Category: Stevens, D J.]]
[[Category: Xaio, B.]]
[[Category: Xaio, B.]]
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[[Category: h7]]
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[[Category: H7]]
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[[Category: haemagglutinin]]
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[[Category: Haemagglutinin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:58:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:56:25 2008''
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Revision as of 06:58, 3 May 2008

Image:1ti8.gif

Template:STRUCTURE 1ti8

H7 Haemagglutinin


Overview

Comparing the structures of H3, H5 and H9 subtype haemagglutinins, we deduced a structural basis for including all 15 influenza subtypes in four clades. H3, H5 and H9 represent three of these clades; we now report the structure of an H7 HA as a representative of the fourth clade. We confirm the structure of the turn at the N-terminus of the conserved central alpha-helix of HA2, and the combination of ionisable residues near the "fusion peptide" as clade-specific features. We compare the structures of three H1 HAs with H5 HA in the same clade, to refine our previous classification and we confirm the division of the clades into two groups of two. We also show the roles of carbohydrate side chains in the esterase-fusion domain boundaries in the formation of clade-specific structural markers.

About this Structure

1TI8 is a Protein complex structure of sequences from Influenza a virus. Full crystallographic information is available from OCA.

Reference

H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes., Russell RJ, Gamblin SJ, Haire LF, Stevens DJ, Xiao B, Ha Y, Skehel JJ, Virology. 2004 Aug 1;325(2):287-96. PMID:15246268 Page seeded by OCA on Sat May 3 09:58:45 2008

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