5ppm

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'''Unreleased structure'''
 
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The entry 5ppm is ON HOLD
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==PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 23)==
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<StructureSection load='5ppm' size='340' side='right' caption='[[5ppm]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
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Authors: Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ppm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5PPM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5PPM FirstGlance]. <br>
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Description: PanDDA analysis group deposition --Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 23)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ppm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ppm OCA], [http://pdbe.org/5ppm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ppm RCSB], [http://www.ebi.ac.uk/pdbsum/5ppm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ppm ProSAT]</span></td></tr>
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[[Category: Pearce, N.M]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Bradley, A R]]
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[[Category: Brandao-Neto, J]]
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[[Category: Brennan, P E]]
[[Category: Collins, P]]
[[Category: Collins, P]]
[[Category: Cox, O]]
[[Category: Cox, O]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Delft, F von]]
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[[Category: Brandao-Neto, J]]
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[[Category: Dias, A]]
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[[Category: Douangamath, A]]
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[[Category: Edwards, A]]
[[Category: Fairhead, M]]
[[Category: Fairhead, M]]
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[[Category: Von Delft, F]]
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[[Category: Krojer, T]]
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[[Category: MacLean, E]]
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[[Category: Ng, J]]
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[[Category: Pearce, N M]]
[[Category: Renjie, Z]]
[[Category: Renjie, Z]]
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[[Category: Sethi, R]]
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[[Category: Talon, R]]
[[Category: Wright, N]]
[[Category: Wright, N]]
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[[Category: Ng, J]]
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[[Category: Bromodomain]]
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[[Category: Bradley, A.R]]
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[[Category: Epigenetic]]
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[[Category: Talon, R]]
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[[Category: Gene regulation]]
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[[Category: Brennan, P.E]]
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[[Category: Pandda]]
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[[Category: Edwards, A]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Douangamath, A]]
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[[Category: Xchemexplorer]]
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[[Category: Maclean, E]]
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[[Category: Krojer, T]]
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[[Category: Dias, A]]
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[[Category: Sethi, R]]
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[[Category: Bountra, C]]
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Revision as of 13:49, 29 March 2017

PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 23)

5ppm, resolution 1.87Å

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