This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5juz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal structure of human FPPS in complex with an allosteric inhibitor CL-06-057==
==Crystal structure of human FPPS in complex with an allosteric inhibitor CL-06-057==
-
<StructureSection load='5juz' size='340' side='right' caption='[[5juz]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+
<StructureSection load='5juz' size='340' side='right'caption='[[5juz]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5juz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JUZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JUZ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5juz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JUZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JUZ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=YL4:[(R)-(2,3-DIHYDRO-1-BENZOFURAN-5-YL){[6-(4-METHYLPHENYL)THIENO[2,3-D]PYRIMIDIN-4-YL]AMINO}METHYL]PHOSPHONIC+ACID'>YL4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=YL4:[(R)-(2,3-DIHYDRO-1-BENZOFURAN-5-YL){[6-(4-METHYLPHENYL)THIENO[2,3-D]PYRIMIDIN-4-YL]AMINO}METHYL]PHOSPHONIC+ACID'>YL4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jv2|5jv2]], [[5jv1|5jv1]], [[5jv0|5jv0]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jv2|5jv2]], [[5jv1|5jv1]], [[5jv0|5jv0]]</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5juz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5juz OCA], [http://pdbe.org/5juz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5juz RCSB], [http://www.ebi.ac.uk/pdbsum/5juz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5juz ProSAT]</span></td></tr>
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5juz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5juz OCA], [http://pdbe.org/5juz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5juz RCSB], [http://www.ebi.ac.uk/pdbsum/5juz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5juz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
Line 19: Line 20:
</div>
</div>
<div class="pdbe-citations 5juz" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5juz" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Human]]
 +
[[Category: Large Structures]]
[[Category: Berghuis, A M]]
[[Category: Berghuis, A M]]
[[Category: Leung, C Y]]
[[Category: Leung, C Y]]

Revision as of 11:40, 17 June 2020

Crystal structure of human FPPS in complex with an allosteric inhibitor CL-06-057

PDB ID 5juz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools