This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5jv1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal structure of human FPPS in complex with an allosteric inhibitor CL-08-066==
==Crystal structure of human FPPS in complex with an allosteric inhibitor CL-08-066==
-
<StructureSection load='5jv1' size='340' side='right' caption='[[5jv1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+
<StructureSection load='5jv1' size='340' side='right'caption='[[5jv1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5jv1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JV1 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5jv1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JV1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JV1 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YL6:[(1R)-1-{[6-(3-CHLORO-4-METHYLPHENYL)THIENO[2,3-D]PYRIMIDIN-4-YL]AMINO}-2-(3-FLUOROPHENYL)ETHYL]PHOSPHONIC+ACID'>YL6</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YL6:[(1R)-1-{[6-(3-CHLORO-4-METHYLPHENYL)THIENO[2,3-D]PYRIMIDIN-4-YL]AMINO}-2-(3-FLUOROPHENYL)ETHYL]PHOSPHONIC+ACID'>YL6</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jv2|5jv2]], [[5jv0|5jv0]], [[5juz|5juz]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jv2|5jv2]], [[5jv0|5jv0]], [[5juz|5juz]]</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jv1 OCA], [http://pdbe.org/5jv1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jv1 RCSB], [http://www.ebi.ac.uk/pdbsum/5jv1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jv1 ProSAT]</span></td></tr>
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jv1 OCA], [http://pdbe.org/5jv1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jv1 RCSB], [http://www.ebi.ac.uk/pdbsum/5jv1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jv1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
Line 19: Line 20:
</div>
</div>
<div class="pdbe-citations 5jv1" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5jv1" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Human]]
 +
[[Category: Large Structures]]
[[Category: Berghuis, A M]]
[[Category: Berghuis, A M]]
[[Category: Leung, C Y]]
[[Category: Leung, C Y]]

Revision as of 11:40, 17 June 2020

Crystal structure of human FPPS in complex with an allosteric inhibitor CL-08-066

PDB ID 5jv1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools