Sandbox Reserved 1066

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==Zn Transporter YiiP==
==Zn Transporter YiiP==
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<StructureSection load='3h90' size='340' side='right' caption='Zn Transporter' scene=''>
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This is a default text for your page '''Kyle Colston/Sandbox 1''<scene name='69/694233/Tm1/1'>TM1</scene>'. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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This is a default text for your page '''Kyle Colston/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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This protein is found in ''E. coli''
This protein is found in ''E. coli''
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==Mechanism for Transport==
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==Structure==
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==Zinc Induced Conformation Change==
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===Zn Induced Conformation Change===
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The ligand binding domains (CTD) and pore domains (TMD) are connected by the flexible loop that houses the charge interlock mechanism that helps hold the homodimer together. This flexible loop also acts as a hinge for the CTDs to come together and bind Zn at active site C. Zn binding to the CTD causes a conformation change in the TMD which ca
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===Allosteric Inhibition===
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==Allosteric Inhibition==
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Zn binding to Active Site C causes a conformation change that reduces the affinity for Zn at Active Site A.
Zn binding to Active Site C causes a conformation change that reduces the affinity for Zn at Active Site A.
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== Function ==
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== Disease ==
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== Relevance ==
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== Structural highlights ==
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

Revision as of 18:28, 24 March 2017

Zn Transporter YiiP

Zn Transporter

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References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
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