Caspase
From Proteopedia
(Difference between revisions)
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**[[1sc1]], [[1sc4]] - hCASP (mutant) <br /> | **[[1sc1]], [[1sc4]] - hCASP (mutant) <br /> | ||
**[[1sc3]] - hCASP (mutant) + malonate<br /> | **[[1sc3]] - hCASP (mutant) + malonate<br /> | ||
| - | **[[3d6f]], [[3d6h]], [[3d6m]], [[1ibc]] - hCASP (mutant) + polypeptide inhibitor<br /> | + | **[[3d6f]], [[3d6h]], [[3d6m]], [[1ibc]], [[5mtk]], [[5mmv]] - hCASP (mutant) + polypeptide inhibitor<br /> |
**[[2hbq]], [[1bmq]], [[3ns7]] - hCASP + inhibitor<br /> | **[[2hbq]], [[1bmq]], [[3ns7]] - hCASP + inhibitor<br /> | ||
**[[2h4w]], [[2h4y]], [[2h51]], [[2h54]], [[2hbr]], [[2hby]], [[2hbz]], [[2h48]], [[2fqq]], [[1rwk]], [[1rwm]], [[1rwn]], [[1rwo]], [[1rwp]], [[1rwv]], [[1rww]], [[1rwx]] - hCASP (mutant) + inhibitor<br /> | **[[2h4w]], [[2h4y]], [[2h51]], [[2h54]], [[2hbr]], [[2hby]], [[2hbz]], [[2h48]], [[2fqq]], [[1rwk]], [[1rwm]], [[1rwn]], [[1rwo]], [[1rwp]], [[1rwv]], [[1rww]], [[1rwx]] - hCASP (mutant) + inhibitor<br /> | ||
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**[[3pcx]], [[3pd1]], [[3pd0]], [[3gjq]], [[3gjr]], [[3gjs]], [[3gjt]], [[3edq]], [[3edr]], [[2cnk]], [[2cnl]], [[2cnn]], [[2cno]], [[2cdr]], [[2h65]], [[1cp3]], [[1pau]], [[4pry]] – hCASP + polypeptide inhibitor<br /> | **[[3pcx]], [[3pd1]], [[3pd0]], [[3gjq]], [[3gjr]], [[3gjs]], [[3gjt]], [[3edq]], [[3edr]], [[2cnk]], [[2cnl]], [[2cnn]], [[2cno]], [[2cdr]], [[2h65]], [[1cp3]], [[1pau]], [[4pry]] – hCASP + polypeptide inhibitor<br /> | ||
**[[4dcj]], [[4dco]], [[4dcp]], [[4eha]], [[4ehd]], [[4ehf]], [[4ehh]], [[4ehk]], [[4ehl]], [[4ehn]], [[4ps0]], [[4ps1]] – hCASP subunits P12, P17 + polypeptide inhibitor<br /> | **[[4dcj]], [[4dco]], [[4dcp]], [[4eha]], [[4ehd]], [[4ehf]], [[4ehh]], [[4ehk]], [[4ehl]], [[4ehn]], [[4ps0]], [[4ps1]] – hCASP subunits P12, P17 + polypeptide inhibitor<br /> | ||
| - | **[[2dko]], [[2cjx]], [[2cjy]], [[4qtx]], [[4qty]], [[4qu0]], [[4qu5]], [[4qu8]], [[4qu9]], [[4qua]], [[4qub]] [[4qud]], [[4que]], [[4qug]], [[4quh]], [[4qui]], [[4quj]], [[4qul]], [[5i9b]], [[5i9t]], [[5iab]], [[5iae]], [[5iag]], [[5iaj]], [[5iak]], [[5ian]], [[5iar]], [[5ias]], [[5ibc]], [[5ibp]], [[5ibr]], [[4qud]] - hCASP (mutant) + polypeptide inhibitor<br /> | + | **[[2dko]], [[2cjx]], [[2cjy]], [[4qtx]], [[4qty]], [[4qu0]], [[4qu5]], [[4qu8]], [[4qu9]], [[4qua]], [[4qub]] [[4qud]], [[4que]], [[4qug]], [[4quh]], [[4qui]], [[4quj]], [[4qul]], [[5i9b]], [[5i9t]], [[5iab]], [[5iae]], [[5iag]], [[5iaj]], [[5iak]], [[5ian]], [[5iar]], [[5ias]], [[5ibc]], [[5ibp]], [[5ibr]], [[4qud]], [[6bfj]], [[6bfk]], [[6bfl]], [[6bfo]], [[6bg0]], [[6bg1]], [[6bg4]], [[6bgk]], [[6bgq]], [[6bgr]], [[6bgs]], [[6bh9]], [[6bha]], [[6bdv]] - hCASP (mutant) + polypeptide inhibitor<br /> |
**[[3kjf]], [[3h0e]], [[3deh]], [[3dei]], [[3dej]], [[3dek]], [[1re1]], [[1rhj]], [[1rhk]], [[1rhm]], [[1rhq]], [[1rhr]], [[1rhu]], [[1nme]], [[1nmq]], [[1nms]], [[1gfw]] – hCASP + inhibitor<br /> | **[[3kjf]], [[3h0e]], [[3deh]], [[3dei]], [[3dej]], [[3dek]], [[1re1]], [[1rhj]], [[1rhk]], [[1rhm]], [[1rhq]], [[1rhr]], [[1rhu]], [[1nme]], [[1nmq]], [[1nms]], [[1gfw]] – hCASP + inhibitor<br /> | ||
**[[3itn]], [[2j30]], [[2j31]], [[2j32]], [[2j33]], [[2c1e]], [[2c2k]], [[2c2m]], [[2c2o]], [[2c2z]], [[2h5i]], [[2h5j]], [[4jr0]] – hpro-CASP + polypeptide inhibitor<br /> | **[[3itn]], [[2j30]], [[2j31]], [[2j32]], [[2j33]], [[2c1e]], [[2c2k]], [[2c2m]], [[2c2o]], [[2c2z]], [[2h5i]], [[2h5j]], [[4jr0]] – hpro-CASP + polypeptide inhibitor<br /> | ||
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**[[3h1p]], [[4jr1]], [[4jr2]] - hCASP catalytic domain (mutant) + polypeptide inhibitor<br /> | **[[3h1p]], [[4jr1]], [[4jr2]] - hCASP catalytic domain (mutant) + polypeptide inhibitor<br /> | ||
**[[1shj]], [[1shl]] - hCASP catalytic domain (mutant) + inhibitor<br /> | **[[1shj]], [[1shl]] - hCASP catalytic domain (mutant) + inhibitor<br /> | ||
| - | **[[4fea]] - hCASP catalytic domain + inhibitor<br /> | + | **[[4fea]], [[5v6z]], [[5v6u]] - hCASP catalytic domain + inhibitor<br /> |
**[[1i51]], [[1kmc]] - hCASP (mutant) + XIAP-BIR2<br /> | **[[1i51]], [[1kmc]] - hCASP (mutant) + XIAP-BIR2<br /> | ||
**[[1i4o]] - hCASP P20 subunit + XIAP<br /> | **[[1i4o]] - hCASP P20 subunit + XIAP<br /> | ||
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**[[5l08]] – hCASP – Cryo-EM<br /> | **[[5l08]] – hCASP – Cryo-EM<br /> | ||
**[[4zbw]] - hCASP death effector domain<br /> | **[[4zbw]] - hCASP death effector domain<br /> | ||
| + | **[[5h33]] - hCASP death effector domain (mutant)<br /> | ||
**[[3kjn]], [[3kjq]] – hCASP subunit P18 + inhibitor<br /> | **[[3kjn]], [[3kjq]] – hCASP subunit P18 + inhibitor<br /> | ||
**[[1f9e]], [[1qtn]], [[1qdu]] - hCASP subunit α,β + polypeptide inhibitor<br /> | **[[1f9e]], [[1qtn]], [[1qdu]] - hCASP subunit α,β + polypeptide inhibitor<br /> | ||
Revision as of 07:07, 8 April 2018
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3D structures of caspase
Updated on 08-April-2018
4jqy, 4jqz - hpro-CASP (mutant)
References
- ↑ Schweizer A, Briand C, Grutter MG. Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway. J Biol Chem. 2003 Oct 24;278(43):42441-7. Epub 2003 Aug 14. PMID:12920126 doi:http://dx.doi.org/10.1074/jbc.M304895200
- ↑ Wilson KP, Black JA, Thomson JA, Kim EE, Griffith JP, Navia MA, Murcko MA, Chambers SP, Aldape RA, Raybuck SA, et al.. Structure and mechanism of interleukin-1 beta converting enzyme. Nature. 1994 Jul 28;370(6487):270-5. PMID:8035875 doi:http://dx.doi.org/10.1038/370270a0
