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5n8c
From Proteopedia
(Difference between revisions)
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==Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor== | ==Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor== | ||
| - | <StructureSection load='5n8c' size='340' side='right' caption='[[5n8c]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='5n8c' size='340' side='right'caption='[[5n8c]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5n8c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N8C OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5n8c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N8C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5N8C FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8Q8:(2~{S})-3-AZANYL-2-[[(1~{R})-5-[2-[4-[[2-(HYDROXYMETHYL)IMIDAZOL-1-YL]METHYL]PHENYL]ETHYNYL]-2,3-DIHYDRO-1~{H}-INDEN-1-YL]AMINO]-3-METHYL-~{N}-OXIDANYL-BUTANAMIDE'>8Q8</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8Q8:(2~{S})-3-AZANYL-2-[[(1~{R})-5-[2-[4-[[2-(HYDROXYMETHYL)IMIDAZOL-1-YL]METHYL]PHENYL]ETHYNYL]-2,3-DIHYDRO-1~{H}-INDEN-1-YL]AMINO]-3-METHYL-~{N}-OXIDANYL-BUTANAMIDE'>8Q8</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-3-O-acyl-N-acetylglucosamine_deacetylase UDP-3-O-acyl-N-acetylglucosamine deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.108 3.5.1.108] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-3-O-acyl-N-acetylglucosamine_deacetylase UDP-3-O-acyl-N-acetylglucosamine deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.108 3.5.1.108] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5n8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n8c OCA], [http://pdbe.org/5n8c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n8c RCSB], [http://www.ebi.ac.uk/pdbsum/5n8c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n8c ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5n8c" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5n8c" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: UDP-3-O-acyl-N-acetylglucosamine deacetylase]] | [[Category: UDP-3-O-acyl-N-acetylglucosamine deacetylase]] | ||
[[Category: Andersen, O A]] | [[Category: Andersen, O A]] | ||
Revision as of 11:59, 26 August 2020
Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor
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