Tryptophan RNA-binding attenuation protein

From Proteopedia

Revision as of 10:32, 30 March 2017

spinqualitylabelsall models Structure of tryptophan RNA-binding attenuation protein complex with Trp (PDB code 2exs). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Tryptophan RNA-binding attenuation protein (TRAP) is a tryptophan-activated RNA-binding protein which regulates the expression of the tryptophan biosynthesis genes. Down regulation of Trp biosynthesis is observed upon binding of 11 Trp to TRAP[1]. Structural highlights TRAP is composed of 11 identical subunits arranged in a symmetrical ring. The [2].

3D Structures of tryptophan RNA-binding attenuation protein

Updated on 30-March-2017

References

1. ↑ Li PT, Gollnick P. Characterization of a trp RNA-binding attenuation protein (TRAP) mutant with tryptophan independent RNA binding activity. J Mol Biol. 2004 Jan 16;335(3):707-22. PMID:14687568 doi:http://dx.doi.org/10.1016/S0022283603013846
2. ↑ Heddle JG, Yokoyama T, Yamashita I, Park SY, Tame JR. Rounding up: Engineering 12-membered rings from the cyclic 11-mer TRAP. Structure. 2006 May;14(5):925-33. PMID:16698553 doi:http://dx.doi.org/10.1016/j.str.2006.03.013