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Crystallin
From Proteopedia
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<StructureSection load='2g98' size='400' side='right' scene='Crystalline/C/1' caption='human γ-D-crystalline, [[2g98]]'> | <StructureSection load='2g98' size='400' side='right' scene='Crystalline/C/1' caption='human γ-D-crystalline, [[2g98]]'> | ||
== Function == | == Function == | ||
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== Disease == | == Disease == | ||
| - | Several human cataracts have been linked to mutations in γ-D-crystalline. | + | Several human cataracts have been linked to mutations in γ-D-crystalline<ref>PMID:11371638</ref>. |
</StructureSection> | </StructureSection> | ||
== 3D Structures of Crystalline == | == 3D Structures of Crystalline == | ||
Revision as of 08:18, 5 April 2017
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3D Structures of Crystalline
Updated on 05-April-2017
2g98 - hγ-D-crystalline – human
1h4a - hγ-D-crystalline (mutant)
1elp - γ-D-crystalline – bovine
1auw - δ-2-crystalline (mutant) - duck
References
- ↑ Basak A, Bateman O, Slingsby C, Pande A, Asherie N, Ogun O, Benedek GB, Pande J. High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract. J Mol Biol. 2003 May 16;328(5):1137-47. PMID:12729747
- ↑ Pande A, Pande J, Asherie N, Lomakin A, Ogun O, King J, Benedek GB. Crystal cataracts: human genetic cataract caused by protein crystallization. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6116-20. PMID:11371638 doi:http://dx.doi.org/10.1073/pnas.101124798
