5kny
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with (3-((3R,4R)-3-(Guanin-9-yl)-4-((S)-2-hydroxy-2-phosphonoethoxy)pyrrolidin-1-yl)-3-oxopropyl)phosphonic acid== | |
| - | + | <StructureSection load='5kny' size='340' side='right' caption='[[5kny]], [[Resolution|resolution]] 2.91Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5kny]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KNY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YPG:[3-[(3~{R},4~{R})-3-(2-AZANYL-6-OXIDANYLIDENE-1~{H}-PURIN-9-YL)-4-[(2~{S})-2-OXIDANYL-2-PHOSPHONO-ETHOXY]PYRROLIDIN-1-YL]-3-OXIDANYLIDENE-PROPYL]PHOSPHONIC+ACID'>YPG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5knp|5knp]], [[5knq|5knq]], [[5knr|5knr]], [[5kns|5kns]], [[5knv|5knv]], [[5knu|5knu]], [[5knt|5knt]], [[5knx|5knx]]</td></tr> |
| - | [[Category: Eng, W | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hpt, hprT, Rv3624c, MTCY15C10.28 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kny OCA], [http://pdbe.org/5kny PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kny RCSB], [http://www.ebi.ac.uk/pdbsum/5kny PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kny ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hypoxanthine phosphoribosyltransferase]] | ||
| + | [[Category: Myctu]] | ||
| + | [[Category: Eng, W S]] | ||
| + | [[Category: Guddat, L W]] | ||
| + | [[Category: Keough, D T]] | ||
[[Category: Rejman, D]] | [[Category: Rejman, D]] | ||
| - | [[Category: | + | [[Category: Complex]] |
| - | [[Category: | + | [[Category: Inhibitor]] |
| + | [[Category: Phosphoribosyltransferase]] | ||
| + | [[Category: Pyrrolidne nucleoside phosphonate]] | ||
| + | [[Category: Transferase-inhibitor complex]] | ||
Revision as of 14:14, 15 November 2017
Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with (3-((3R,4R)-3-(Guanin-9-yl)-4-((S)-2-hydroxy-2-phosphonoethoxy)pyrrolidin-1-yl)-3-oxopropyl)phosphonic acid
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